Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CDK4 | P11802 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MC5R | P33032 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3867784 | 0.88 | SLC6A4 (0.54) | MAPTALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL3867782 | 0.88 | SLC6A4 (0.54) | MAPTALDH1A1CYP2C19KMT2AMEN1 | |
| Indolylpropionic Acid SCHEMBL195405 | 0.87 | MAPT (0.68) | MAPTALDH1A1GAAPDPK1HPGD | |
| Indolylpropionic Acid SCHEMBL29521227 | 0.87 | MAPT (0.68) | MAPTALDH1A1GAAPDPK1HPGD | |
| Indolylpropionic Acid SCHEMBL29374161 | 0.87 | MAPT (0.68) | MAPTALDH1A1GAAPDPK1HPGD | |
| Indolylpropionic Acid SCHEMBL29272702 | 0.86 | MAPT (0.66) | MAPTALDH1A1GAAPDPK1HPGD | |
| Indolylpropionic Acid SCHEMBL2115660 | 0.86 | MAPT (0.66) | MAPTALDH1A1GAAPDPK1HPGD | |
| SCHEMBL30952641 | 0.83 | HTR2A (0.57) | MAPTALDH1A1GAAHPGDCYP2C19 | |
| Indolylpropionic Acid SCHEMBL195854 | 0.82 | MAPT (0.61) | MAPTALDH1A1GAAPDPK1HPGD | |
| SCHEMBL35884 | 0.82 | MEN1 (0.68) | MAPTALDH1A1GAAPDPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2945959-A1 | STABLE INDOLE-3-PROPIONATE SALTS OF S-ADENOSYL-L-METHIONINE | Hebert Sam-E LLC (US) | 2015-11-25 | — | — | EP | disclosed |
| WO-2014113609-A1 | STABLE INDOLE-3-PROPIONATE SALTS OF S-ADENOSYL-L-METHIONINE | HEBERT SAM-E LLC (US) | 2014-07-24 | — | — | WO | disclosed |