Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3867782 | 1.00 | SLC6A4 (0.54) | SLC6A4MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL30952641 | 0.89 | HTR2A (0.57) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| Indolylpropionic Acid SCHEMBL15880225 | 0.88 | MAPT (0.54) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL917538 | 0.85 | MC5R (0.59) | MEN1KMT2ACYP1A2HTR2AHTR1A | |
| SCHEMBL7004146 | 0.83 | HTR2A (0.71) | SLC6A4MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL13255471 | 0.83 | HTR1A (0.58) | SLC6A4KMT2AHTR1BHTR2AHTR2C | |
| SCHEMBL7004071 | 0.82 | HTR2A (0.69) | SLC6A4MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL7889427 | 0.82 | HTR2A (0.69) | SLC6A4MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL7001306 | 0.82 | HTR2A (0.69) | SLC6A4MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL7005718 | 0.80 | HTR2A (0.71) | SLC6A4MEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436938-A | Impurity in indocyanine green medicament and preparation method and application thereof | 南京诺源医疗器械有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-107709323-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2020-11-20 | — | — | CN | disclosed |
| US-10278973-B2 | Hydroxyl purine compounds and use thereof | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2019-05-07 | — | — | US | disclosed |
| CN-107709323-A | Oxipurinol class compound and its application | 广东众生药业股份有限公司 | 2018-02-16 | — | — | CN | disclosed |
| EP-2850061-A2 | HALOGENATED COMPOUNDS FOR PHOTODYNAMIC THERAPY | Nanoquantum Sciences Inc. (US) | 2015-03-25 | — | — | EP | disclosed |
| WO-2013134081-A2 | HALOGENATED COMPOUNDS FOR PHOTODYNAMIC THERAPY | NANOQUANTUM SCIENCES. INC. (US) | 2013-09-12 | — | — | WO | disclosed |
| EP-2046895-A2 | ASYMMETRIC FLUORO-SUBSTITUTED POLYMETHINE DYES | GE Healthcare AS (NO) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008015415-A2 | ASYMMETRIC FLUORO-SUBSTITUTED POLYMETHINE DYES | GE HEALTHCARE AS (NO) | 2008-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10278973-B2 | Hydroxyl purine compounds and use thereof | PNP, PDE7A, PDE2A | SLC6A4 1094/4885MEN1 3692/4885KMT2A 3576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.