Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31180981 | 0.83 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL15897488 | 0.81 | SLC6A3 (0.60) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL31180955 | 0.79 | KMT2A (0.49) | KMT2AMEN1SMN1; SMN2ALDH1A1SLC6A3 | |
| SCHEMBL31181078 | 0.79 | KMT2A (0.49) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL29805952 | 0.77 | KMT2A (0.56) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL4085546 | 0.77 | KMT2A (0.56) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL29139940 | 0.77 | KMT2A (0.64) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL2540179 | 0.77 | CTNNB1 (0.62) | KMT2AMEN1SMN1; SMN2HTTSLC6A3 | |
| SCHEMBL2441955 | 0.77 | SLC6A3 (0.65) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8782253 | 0.76 | SLC6A3 (0.61) | KMT2AMEN1SMN1; SMN2ALDH1A1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140213538-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. | 2014-07-31 | — | — | US | disclosed |
| WO-2014113485-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. (US) | 2014-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213538-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | LPAR1, LPAR2, LPAR5 | KMT2A 2450/4885MEN1 1384/4885SMN1; SMN2 3450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.