Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29805952 | 1.00 | KMT2A (0.56) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL18284643 | 0.85 | ALDH1A1 (0.60) | KMT2AMEN1SMN1; SMN2ALDH1A1SLC6A3 | |
| SCHEMBL30024556 | 0.85 | LMNA (0.47) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL3983758 | 0.85 | LMNA (0.47) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL29805855 | 0.83 | HTT (0.50) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL15880384 | 0.83 | KMT2A (0.60) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL4318924 | 0.81 | ALDH1A1 (0.69) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL2441955 | 0.79 | SLC6A3 (0.65) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL15880378 | 0.77 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL9384288 | 0.77 | ALDH1A1 (0.68) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300879-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2021-09-30 | — | — | US | claimed |
| US-11053204-B2 | Pyrimidinyloxy benzene derivatives as herbicides | FMC CORPORATION (US) | 2021-07-06 | — | — | US | claimed |
| US-20180105501-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORPORATION | 2018-04-19 | — | — | US | claimed |
| EP-3303305-A1 | 2-(PHENYLOXY OR PHENYLTHIO)PYRIMIDINE DERIVATIVES AS HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2018-04-11 | — | — | EP | claimed |
| WO-2016196606-A1 | 2-(PHENYLOXY OR PHENYLTHIO)PYRIMIDINE DERIVATIVES AS HERBICIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2016-12-08 | — | — | WO | claimed |
| CN-115785000-A | 2- (phenoxy or phenylthio) pyrimidine derivatives as herbicides, compositions thereof and methods of controlling undesirable vegetation therewith | FMC公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-107635974-B | 2- (phenoxy or phenylthio) pyrimidine derivatives as herbicides | FMC公司 | 2022-12-20 | — | — | CN | disclosed |
| EP-3303305-B9 | 2-(PHENYLOXY OR PHENYLTHIO)PYRIMIDINE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2022-07-13 | — | — | EP | disclosed |
| EP-3943486-A1 | 2-(PHENYLOXY OR PHENYLTHIO)PYRIMIDINE DERIVATIVES AS HERBICIDES | FMC Corporation (US) | 2022-01-26 | — | — | EP | disclosed |
| EP-3303305-B1 | 2-(PHENYLOXY OR PHENYLTHIO)PYRIMIDINE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2022-01-05 | — | — | EP | disclosed |
| US-20210300879-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2021-09-30 | — | — | US | disclosed |
| US-11053204-B2 | Pyrimidinyloxy benzene derivatives as herbicides | FMC CORPORATION (US) | 2021-07-06 | — | — | US | disclosed |
| US-20180105501-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORPORATION | 2018-04-19 | — | — | US | disclosed |
| EP-3303305-A1 | 2-(PHENYLOXY OR PHENYLTHIO)PYRIMIDINE DERIVATIVES AS HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016196606-A1 | 2-(PHENYLOXY OR PHENYLTHIO)PYRIMIDINE DERIVATIVES AS HERBICIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2016-12-08 | — | — | WO | disclosed |
| US-20090291971-A1 | HETEROARYL ETHERS AND PROCESSES FOR THEIR PREPARATION | WYETH (US) | 2009-11-26 | — | — | US | disclosed |
| US-20090291971-A1 | HETEROARYL ETHERS AND PROCESSES FOR THEIR PREPARATION | WYETH (US) | 2009-11-26 | — | — | US | disclosed |
| US-20090291971-A1 | HETEROARYL ETHERS AND PROCESSES FOR THEIR PREPARATION | WYETH (US) | 2009-11-26 | — | — | US | disclosed |
| WO-2009058937-A2 | HETEROARYL ETHERS AND PROCESSES FOR THEIR PREPARATION | WYETH (US) | 2009-05-07 | — | — | WO | disclosed |
| WO-2009058937-A2 | HETEROARYL ETHERS AND PROCESSES FOR THEIR PREPARATION | WYETH (US) | 2009-05-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105501-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | DDT, CBR3, CYP1B1 | KMT2A 2573/4885MEN1 4156/4885SMN1; SMN2 4327/4885 |
| US-11053204-B2 | Pyrimidinyloxy benzene derivatives as herbicides | DDT, CBR3, CYP1B1 | KMT2A 2573/4885MEN1 4156/4885SMN1; SMN2 4327/4885 |
| US-20210300879-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | DDT, CBR3, CYP1B1 | KMT2A 2573/4885MEN1 4156/4885SMN1; SMN2 4327/4885 |
| US-20090291971-A1 | HETEROARYL ETHERS AND PROCESSES FOR THEIR PREPARATION | AHR, MALT1, ABL1 | KMT2A 620/4885MEN1 1922/4885SMN1; SMN2 3057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.