Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | JUN | P05412 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1589618 | 0.89 | KDM4E (0.73) | MAOBKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL1589619 | 0.89 | KDM4E (0.73) | MAOBKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL29503043 | 0.89 | KDM4E (0.73) | MAOBKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL2026115 | 0.86 | MAOB (0.64) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL7821694 | 0.86 | KDM4E (0.79) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL2026116 | 0.86 | MAOB (0.64) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL6782737 | 0.86 | KDM4E (0.79) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL9403951 | 0.85 | FDPS (0.52) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL9403950 | 0.85 | FDPS (0.52) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL25853485 | 0.84 | FDPS (0.65) | MAOBMAOAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519511-B1 | NOVEL PIPERINE DERIVATIVES AS GABA-A RECEPTORS MODULATORS | Universität Wien (AT) | 2015-12-16 | — | — | EP | disclosed |