Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CCR10 | P46092 | 2/20 | 0.31 |
| ▸ | TYMP | P19971 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.30 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14822353 | 0.92 | CA12 (0.39) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL18589129 | 0.82 | CA12 (0.38) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL16285938 | 0.81 | CA12 (0.41) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL18633388 | 0.80 | CA12 (0.39) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL15899355 | 0.79 | CA12 (0.44) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL14822596 | 0.79 | CA12 (0.44) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL28634383 | 0.79 | CA12 (0.49) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL29705195 | 0.76 | CA12 (0.37) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL10047554 | 0.76 | STAT3 (0.37) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL27794804 | 0.75 | CA12 (0.46) | CA12CA1CA2CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2759538-B1 | RADIOACTIVE FLUORINE LABELED COMPOUND | NIHON MEDIPHYSICS CO LTD (JP) | 2016-03-23 | — | — | EP | disclosed |
| EP-2759538-B1 | RADIOACTIVE FLUORINE LABELED COMPOUND | NIHON MEDIPHYSICS CO LTD (JP) | 2016-03-23 | — | — | EP | disclosed |
| US-9107964-B2 | Radioactive fluorine-labeled compound | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2015-08-18 | — | — | US | disclosed |
| US-9107964-B2 | Radioactive fluorine-labeled compound | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2015-08-18 | — | — | US | disclosed |
| US-20140364620-A1 | RADIOACTIVE FLUORINE-LABELED COMPOUND | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2014-12-11 | — | — | US | disclosed |
| US-20140364620-A1 | RADIOACTIVE FLUORINE-LABELED COMPOUND | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2014-12-11 | — | — | US | disclosed |
| EP-2759538-A1 | RADIOACTIVE FLUORINE LABELED COMPOUND | Nihon Medi-Physics Co., Ltd. (JP) | 2014-07-30 | — | — | EP | disclosed |
| EP-2759538-A1 | RADIOACTIVE FLUORINE LABELED COMPOUND | Nihon Medi-Physics Co., Ltd. (JP) | 2014-07-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364620-A1 | RADIOACTIVE FLUORINE-LABELED COMPOUND | AFF1, PRMT1, DOT1L | CA12 1215/4885CA1 667/4885CA2 2376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.