SCHEMBL14822353

SCHEMBL14822353

Cc1ccc(S(=O)(=O)OCC2(Cn3ccnc3[N+](=O)[O-])COC(C)(C)OC2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 5/20 0.39
▸ CA1 P00915 5/20 0.39
▸ CA2 P00918 5/20 0.39
▸ CA9 Q16790 5/20 0.39
▸ KMT2A Q03164 2/20 0.33
▸ TYMP P19971 3/20 0.32
▸ CYP3A4 P08684 1/20 0.32
▸ CYP2D6 P10635 1/20 0.32
▸ OPRK1 P41145 1/20 0.32
▸ LMNA P02545 2/20 0.32
▸ THRB P10828 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32
▸ HSP90AA1 P07900 1/20 0.32
▸ CXCR5 P32302 1/20 0.32
▸ APLNR P35414 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ CCR6 P51684 1/20 0.32
▸ GFER P55789 1/20 0.32
▸ NOS1 P29475 1/20 0.31
▸ PAX8 Q06710 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15899140 0.92 CA12 (0.41) CA12CA1CA2CA9KMT2A
SCHEMBL18589129 0.90 CA12 (0.38) CA12CA1CA2CA9KMT2A
SCHEMBL18633388 0.88 CA12 (0.39) CA12CA1CA2CA9KMT2A
SCHEMBL29705195 0.83 CA12 (0.37) CA12CA1CA2CA9KMT2A
SCHEMBL18577905 0.82 CYP3A4 (0.34) CA12CA1CA2CA9CYP3A4
SCHEMBL18577912 0.81 CA12 (0.39) CA12CA1CA2CA9KMT2A
SCHEMBL18577891 0.81 CYP1A2 (0.33) CA12CA1CA2CA9CYP3A4
SCHEMBL18577886 0.81 CYP1A2 (0.33) CA12CA1CA2CA9CYP3A4
SCHEMBL18577916 0.81 CYP1A2 (0.33) CA12CA1CA2CA9CYP3A4
SCHEMBL15899135 0.81 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4282857-B1 RADIOACTIVE HALOGEN-LABELED PRECURSOR COMPOUND INST OF SCIENCE TOKYO (JP) 2026-04-15 — — EP disclosed
US-20240034721-A1 RADIOACTIVE HALOGEN LABELING PRECURSOR COMPOUND TOKYO INSTITUTE OF TECHNOLOGY (JP) 2024-02-01 — — US disclosed
EP-4282857-A1 RADIOACTIVE HALOGEN-LABELED PRECURSOR COMPOUND Tokyo Institute of Technology (JP) 2023-11-29 — — EP disclosed
US-11318216-B2 Method for producing radiohalogen-labeled compound and method for producing radiopharmaceutical NIHON MEDI-PHYSICS CO., LTD. (JP) 2022-05-03 — — US disclosed
EP-3536686-B1 METHOD FOR PRODUCING A RADIOPHARMACEUTICAL COMPOSITION NIHON MEDIPHYSICS CO LTD (JP) 2021-11-24 — — EP disclosed
US-10703726-B2 Method for producing radiopharmaceutical composition NIHON MEDI-PHYSICS CO., LTD. (JP) 2020-07-07 — — US disclosed
EP-3643710-A1 PRODUCTION METHOD FOR RADIOHALOGEN-LABELED COMPOUND AND PRODUCTION METHOD FOR RAIDOPHARMACEUTICAL Nihon Medi-Physics Co., Ltd. (JP) 2020-04-29 — — EP disclosed
US-20200121811-A1 METHOD FOR PRODUCING RADIOHALOGEN-LABELED COMPOUND AND METHOD FOR PRODUCING RADIOPHARMACEUTICAL NIHON MEDI-PHYSICS CO., LTD. (JP) 2020-04-23 — — US disclosed
CN-110809575-A Method for producing radioactive halogen-labeled compound and method for producing radiopharmaceutical 日本医事物理股份有限公司 2020-02-18 — — CN disclosed
US-20190276411-A1 Method for Producing Radiopharmaceutical Composition NIHON MEDI-PHYSICS CO., LTD. (JP) 2019-09-12 — — US disclosed
US-20170066748-A1 RADIOACTIVE FLUORINE LABELING PRECURSOR COMPOUND AND METHOD FOR MANUFACTURING RADIOACTIVE FLUORINE LABELED COMPOUND USING THE SAME NIHON MEDI-PHYSICS CO., LTD. (JP) 2017-03-09 — — US disclosed
EP-2759538-B1 RADIOACTIVE FLUORINE LABELED COMPOUND NIHON MEDIPHYSICS CO LTD (JP) 2016-03-23 — — EP disclosed
EP-2759538-B1 RADIOACTIVE FLUORINE LABELED COMPOUND NIHON MEDIPHYSICS CO LTD (JP) 2016-03-23 — — EP disclosed
US-9107964-B2 Radioactive fluorine-labeled compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2015-08-18 — — US disclosed
US-9107964-B2 Radioactive fluorine-labeled compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2015-08-18 — — US disclosed
US-20140364620-A1 RADIOACTIVE FLUORINE-LABELED COMPOUND NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2014-12-11 — — US disclosed
US-20140364620-A1 RADIOACTIVE FLUORINE-LABELED COMPOUND NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2014-12-11 — — US disclosed
EP-2759538-A1 RADIOACTIVE FLUORINE LABELED COMPOUND Nihon Medi-Physics Co., Ltd. (JP) 2014-07-30 — — EP disclosed
EP-2759538-A1 RADIOACTIVE FLUORINE LABELED COMPOUND Nihon Medi-Physics Co., Ltd. (JP) 2014-07-30 — — EP disclosed
WO-2013042668-A1 RADIOACTIVE FLUORINE LABELED COMPOUND 日本メジフィジックス株式会社 (JP) 2013-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140364620-A1 RADIOACTIVE FLUORINE-LABELED COMPOUND AFF1, PRMT1, DOT1L CA12 1215/4885CA1 667/4885CA2 2376/4885
US-20240034721-A1 RADIOACTIVE HALOGEN LABELING PRECURSOR COMPOUND GPR119, SLC5A2, GCKR CA12 616/4885CA1 1611/4885CA2 2854/4885
US-11318216-B2 Method for producing radiohalogen-labeled compound and method for producing radiopharmaceutical RER1, MLX, MRPL21 CA12 2858/4885CA1 3679/4885CA2 4066/4885
US-10703726-B2 Method for producing radiopharmaceutical composition NAA15, TMEM14C, FLNA CA12 1974/4885CA1 3521/4885CA2 2455/4885
US-20190276411-A1 Method for Producing Radiopharmaceutical Composition NAA15, TMEM14C, FLNA CA12 1974/4885CA1 3521/4885CA2 2455/4885
US-20170066748-A1 RADIOACTIVE FLUORINE LABELING PRECURSOR COMPOUND AND METHOD FOR MANUFACTURING RADIOACTIVE FLUORINE LABELED COMPOUND USING THE SAME AFF1, NPFFR1, AFF2 CA12 535/4885CA1 3259/4885CA2 3956/4885
US-20200121811-A1 METHOD FOR PRODUCING RADIOHALOGEN-LABELED COMPOUND AND METHOD FOR PRODUCING RADIOPHARMACEUTICAL RER1, MLX, MRPL21 CA12 2858/4885CA1 3679/4885CA2 4066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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