Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CCR10 | P46092 | 2/20 | 0.32 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14822353 | 0.88 | CA12 (0.39) | CA12CA1CA2CA9NOS1 | |
| SCHEMBL18589129 | 0.86 | CA12 (0.38) | CA12CA1CA2CA9LMNA | |
| SCHEMBL18577905 | 0.85 | CYP3A4 (0.34) | CA12CA1CA2CA9NOS1 | |
| SCHEMBL18607327 | 0.85 | NOS1 (0.36) | CA12CA1CA2CA9NOS1 | |
| SCHEMBL18577886 | 0.84 | CYP1A2 (0.33) | CA12CA1CA2CA9NOS1 | |
| SCHEMBL18577891 | 0.84 | CYP1A2 (0.33) | CA12CA1CA2CA9NOS1 | |
| SCHEMBL18577922 | 0.84 | CYP1A2 (0.33) | CA12CA1CA2CA9NOS1 | |
| SCHEMBL18577916 | 0.84 | CYP1A2 (0.33) | CA12CA1CA2CA9NOS1 | |
| SCHEMBL18589191 | 0.83 | CA12 (0.32) | CA12CA1CA2CA9 | |
| SCHEMBL18577895 | 0.81 | HDAC1 (0.35) | CA12CA1CA2CA9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141537-A1 | RADIOACTIVE FLUORINE LABELING PRECURSOR COMPOUND AND METHOD FOR MANUFACTURING RADIOACTIVE FLUORINE LABELED COMPOUND USING THE SAME | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2017-03-15 | — | — | EP | disclosed |