SCHEMBL15899372

SCHEMBL15899372

CCOCCC(C)CCOC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
TSHR P16473 2/20 0.42
ALOX15 P16050 1/20 0.41
THRB P10828 1/20 0.37
CHRNB2 P17787 4/20 0.33
CHRNA4 P43681 4/20 0.33
CHRNB4 P30926 3/20 0.33
CHRNA3 P32297 3/20 0.33
ACE2 Q9BYF1 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15899283 0.91 TSHR (0.40) ALDH1A1TSHRALOX15THRBACE2
SCHEMBL3088926 0.87 ALOX15 (0.48) ALOX15CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL4444751 0.81 ALOX15 (0.40) ALOX15CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL15218457 0.80 ALDH1A1 (0.43) ALDH1A1TSHRALOX15THRBTDP1
SCHEMBL18224036 0.79 ALOX15 (0.43) ALDH1A1ALOX15CHRNB2CHRNA4CHRNB4
SCHEMBL303904 0.78
SCHEMBL7178816 0.77 MAPT (0.41) ALDH1A1TSHRALOX15ACE2TDP1
SCHEMBL5478948 0.76 ALDH1A1 (0.62) ALDH1A1TSHRALOX15THRB
SCHEMBL5487104 0.76 ALDH1A1 (0.62) ALDH1A1TSHRALOX15THRB
SCHEMBL31474558 0.76 ALDH1A1 (0.62) ALDH1A1TSHRALOX15THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2759552-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO LTD (JP) 2016-02-10 EP disclosed
US-9243081-B2 Solid catalyst component for polymerization of olefin, catalyst for polymerization of olefin, and method for producing olefin polymer TOHO TITANIUM CO., LTD. (JP) 2016-01-26 US disclosed
US-20140343237-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO., LTD. (JP) 2014-11-20 US disclosed
EP-2759552-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER Toho Titanium CO., LTD. (JP) 2014-07-30 EP disclosed