Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | ADH1B | P00325 | 1/20 | 0.52 |
| ▸ | ADH1C | P00326 | 1/20 | 0.52 |
| ▸ | ADH1A | P07327 | 1/20 | 0.52 |
| ▸ | ADH7 | P40394 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15899383 | 1.00 | ALDH1A1 (0.62) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL20587799 | 0.85 | ALDH1A1 (0.61) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL28831662 | 0.85 | ALDH1A1 (0.61) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL15905318 | 0.84 | ALDH1A1 (0.61) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL17320379 | 0.84 | ALDH1A1 (0.61) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL15903179 | 0.82 | ALDH1A1 (0.51) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL17320382 | 0.82 | ALDH1A1 (0.51) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL21095911 | 0.81 | ALDH1A1 (0.54) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL17320383 | 0.80 | HDAC1 (0.46) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL17313339 | 0.80 | HDAC1 (0.46) | ALDH1A1RAB9ANPC1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329268-B2 | Processes for preparing medicaments for the treatment of cardiovascular diseases and intermediates for use therein | BIAL-PORTELA & CA, S.A. (PT) | 2019-06-25 | — | — | US | disclosed |
| US-9376387-B2 | Oxidisable pyridine derivatives, their preparation and use as anti-alzheimer agents | INSA INST NAT DES SCIENCES APPLIQUEES DE ROUEN (FR) | 2016-06-28 | — | — | US | disclosed |
| US-9376387-B2 | Oxidisable pyridine derivatives, their preparation and use as anti-alzheimer agents | INSA INST NAT DES SCIENCES APPLIQUEES DE ROUEN (FR) | 2016-06-28 | — | — | US | disclosed |
| US-9376387-B2 | Oxidisable pyridine derivatives, their preparation and use as anti-alzheimer agents | INSA INST NAT DES SCIENCES APPLIQUEES DE ROUEN (FR) | 2016-06-28 | — | — | US | disclosed |
| US-20150353493-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | INSA (INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE ROUEN (FR) | 2015-12-10 | — | — | US | disclosed |
| US-20150353493-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | INSA (INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE ROUEN (FR) | 2015-12-10 | — | — | US | disclosed |
| US-20150353493-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | INSA (INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE ROUEN (FR) | 2015-12-10 | — | — | US | disclosed |
| EP-2948429-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | INSA (Institut National des Sciences Appliquees) de Rouen (FR) | 2015-12-02 | — | — | EP | disclosed |
| WO-2014114742-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | INSA (INSTITUT NATIONAL DES SCIENCES APPLIQUÉES) DE ROUEN (FR) | 2014-07-31 | — | — | WO | disclosed |
| EP-2759536-A1 | Oxidisable pyridine derivatives, their preparation and use as anti-Alzheimer agents | INSA (Institut National des Sciences Appliquees) de Rouen (FR) | 2014-07-30 | — | — | EP | disclosed |
| EP-2759536-A1 | Oxidisable pyridine derivatives, their preparation and use as anti-Alzheimer agents | INSA (Institut National des Sciences Appliquees) de Rouen (FR) | 2014-07-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353493-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | CBR3, CBR1, CYB5R3 | ALDH1A1 3811/4885RAB9A 2078/4885NPC1 748/4885 |
| US-10329268-B2 | Processes for preparing medicaments for the treatment of cardiovascular diseases and intermediates for use therein | DBH, COMT, ADRB3 | ALDH1A1 190/4885RAB9A 3867/4885NPC1 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.