Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.49 |
| ▸ | UTRN | P46939 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15899728 | 0.77 | S1PR1 (0.51) | S1PR1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3726997 | 0.77 | HDAC3 (0.49) | S1PR1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3727000 | 0.77 | HDAC3 (0.49) | S1PR1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10882865 | 0.76 | S1PR1 (0.61) | S1PR1S1PR3HPSE | |
| SCHEMBL25138775 | 0.75 | HDAC1 (0.59) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL26686864 | 0.75 | NPC1 (0.59) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL934424 | 0.74 | HDAC1 (0.58) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL2092316 | 0.73 | HDAC3 (0.63) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL2247289 | 0.73 | RAB9A (0.74) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL15437219 | 0.73 | HDAC3 (0.53) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986633-B1 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORP PLC (GB) | 2014-07-30 | — | — | EP | claimed |