Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16263088 | 0.95 | FOLH1 (0.48) | FOLH1SIGMAR1CA2MAPK1GRIK1 | |
| SCHEMBL15900035 | 0.87 | FOLH1 (0.52) | FOLH1CA2MAPK1GRIK1GRIK2 | |
| SCHEMBL11674952 | 0.84 | CA2 (0.57) | FOLH1SIGMAR1CA2MAPK1GRIK1 | |
| SCHEMBL27914221 | 0.82 | FOLH1 (0.47) | FOLH1CA2MAPK1GRIK1GRIK2 | |
| SCHEMBL15640198 | 0.81 | CA2 (0.40) | FOLH1SIGMAR1CA2MAPK1GRIK1 | |
| SCHEMBL29217 | 0.80 | FOLH1 (0.68) | FOLH1CA2MAPK1TDP1 | |
| SCHEMBL8587841 | 0.79 | CA2 (0.61) | SIGMAR1CA2MAPK1GRIK1GRIK2 | |
| Nonic Acid SCHEMBL29394883 | 0.79 | CA2 (0.59) | FOLH1CA2MAPK1GRIK1GRIK2 | |
| Nonic Acid SCHEMBL706231 | 0.79 | CA2 (0.59) | FOLH1CA2MAPK1GRIK1GRIK2 | |
| Nonic Acid SCHEMBL29949536 | 0.79 | CA2 (0.59) | FOLH1CA2MAPK1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2759547-B1 | PLATINUM COMPOUND HAVING AMINO- OR ALKYLAMINO-CONTAINING SUCCINIC ACID DERIVATIVES AS LEAVING GROUP, PREPARATION METHOD THEREFOR, AND USE THEREOF | BEIJING FSWELCOME TECH DEV CO LTD (CN) | 2017-01-18 | — | — | EP | claimed |
| EP-2759547-A1 | PLATINUM COMPOUND HAVING AMINO- OR ALKYLAMINO-CONTAINING SUCCINIC ACID DERIVATIVES AS LEAVING GROUP, PREPARATION METHOD THEREFOR, AND USE THEREOF | Beijing Fswelcome Technology Development Co., Ltd (CN) | 2014-07-30 | — | — | EP | claimed |
| EP-2759547-B1 | PLATINUM COMPOUND HAVING AMINO- OR ALKYLAMINO-CONTAINING SUCCINIC ACID DERIVATIVES AS LEAVING GROUP, PREPARATION METHOD THEREFOR, AND USE THEREOF | BEIJING FSWELCOME TECH DEV CO LTD (CN) | 2017-01-18 | — | — | EP | disclosed |
| US-9175024-B2 | Platinum compound having amino or alkylamino-containing succinic acid derivatives as leaving group, preparation method thereof, and use thereof | BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2015-11-03 | — | — | US | disclosed |
| US-20140349985-A1 | PLATINUM COMPOUND HAVING AMINO OR ALKYLAMINO-CONTAINING SUCCINIC ACID DERIVATIVES AS LEAVING GROUP, PREPARTION METHOD THEREOF, AND USE THEREOF | BEIJING SHOWBY PHARMACEUTICAL CO., LTD. (CN) | 2014-11-27 | — | — | US | disclosed |
| EP-2759547-A1 | PLATINUM COMPOUND HAVING AMINO- OR ALKYLAMINO-CONTAINING SUCCINIC ACID DERIVATIVES AS LEAVING GROUP, PREPARATION METHOD THEREFOR, AND USE THEREOF | Beijing Fswelcome Technology Development Co., Ltd (CN) | 2014-07-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140349985-A1 | PLATINUM COMPOUND HAVING AMINO OR ALKYLAMINO-CONTAINING SUCCINIC ACID DERIVATIVES AS LEAVING GROUP, PREPARTION METHOD THEREOF, AND USE THEREOF | SLC7A5, SLC43A1, SLC7A1 | FOLH1 104/4885SIGMAR1 4219/4885CA2 1746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.