Phenylalanine

Phenylalanine

SCHEMBL15901818

NC(=O)CC[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O.O=C(O)[C@@H]1CCCN1.O=C(O)[C@@H]1CCCN1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Phenylalanine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.49
ALPI P09923 1/20 0.49
PKM P14618 1/20 0.49
PTGS1 P23219 1/20 0.49
XIAP P98170 1/20 0.49
CTSC P53634 2/20 0.46
ALOX15 P16050 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
KMT2A Q03164 1/20 0.42
SLC1A3 P43003 2/20 0.40
SLC1A2 P43004 2/20 0.40
SLC1A1 P43005 2/20 0.40
ACE P12821 1/20 0.40
DPP4 P27487 2/20 0.39
DPP8 Q6V1X1 2/20 0.39
DPP9 Q86TI2 2/20 0.39
DPP7 Q9UHL4 2/20 0.39
SLC15A1 P46059 1/20 0.39
FAP Q12884 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylalanine SCHEMBL3100357 0.96 SLC7A5 (0.45) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL22231291 0.93 ALPI (0.42) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL28179550 0.91 SLC7A5 (0.51) SLC7A5ALPIPKMPTGS1XIAP
D-Phenylalanine SCHEMBL2184336 0.91 SLC7A5 (0.59) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL22468204 0.91 SLC7A5 (0.59) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL148429 0.91 SLC7A5 (0.59) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL2478801 0.91 SLC7A5 (0.59) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL2478802 0.91 SLC7A5 (0.59) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL498385 0.91 SLC7A5 (0.59) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL28136484 0.91 SLC7A5 (0.59) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730179-B2 Gluten-free starch and methods of producing the same MANILDRA MILLING CORPORATION (US) 2023-08-22 US disclosed
WO-2019073083-A2 BETA-GLUCAN COMPOSITIONS TATE & LYLE SWEDEN AB (SE) 2019-04-18 WO disclosed
EP-3313199-A1 GLUTEN-FREE STARCH AND METHODS OF PRODUCING SAME Manildra Milling Corporation (US) 2018-05-02 EP disclosed
WO-2016210408-A1 GLUTEN-FREE STARCH AND METHODS OF PRODUCING SAME MANILDRA MILLING CORPORATION (US) 2016-12-29 WO disclosed
US-20160374374-A1 GLUTEN-FREE STARCH AND METHODS OF PRODUCING THE SAME MANILDRA MILLING CORPORATION 2016-12-29 US disclosed
US-20140212542-A1 Method For Producing Gluten-Free Vodka From Gluten Sources MINHAS MANHOMAN SINGH (BB) 2014-07-31 US disclosed