Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phenylalanine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | ALPI | P09923 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | XIAP | P98170 | 1/20 | 0.59 |
| ▸ | CTSC | P53634 | 2/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 3/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.45 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Phenylalanine SCHEMBL498385 | 1.00 | SLC7A5 (0.59) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL22468204 | 1.00 | SLC7A5 (0.59) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine SCHEMBL28136484 | 1.00 | SLC7A5 (0.59) | SLC7A5PTGS1ALPIPKMXIAP | |
| D-Phenylalanine SCHEMBL2184336 | 1.00 | SLC7A5 (0.59) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine SCHEMBL2478802 | 1.00 | SLC7A5 (0.59) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL2478801 | 1.00 | SLC7A5 (0.59) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL5134569 | 1.00 | SLC7A5 (0.59) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL21899689 | 0.95 | SLC7A5 (0.54) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine SCHEMBL4405170 | 0.95 | SLC7A5 (0.54) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL21899690 | 0.95 | SLC7A5 (0.54) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 399 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118304208-A | Use of cyclic dipeptides for skin whitening | 陕西慧康生物科技有限责任公司 | 2024-07-09 | — | — | CN | claimed |
| CN-117165644-A | Culture method for producing cyclic dipeptide from monascus | 福建永春侨新酿造有限责任公司 | 2023-12-05 | — | — | CN | claimed |
| CN-107312068-B | Fluorescent probe for detecting activity of proline isomerase, preparation and application thereof | 浙江大学 | 2021-02-09 | — | — | CN | claimed |
| CN-108120838-B | Dipeptide derivative for detecting angiotensin II and preparation method and application thereof | 苏州博源医疗科技有限公司 | 2020-06-30 | — | — | CN | claimed |
| CN-107312068-A | A kind of fluorescence probe for detecting proline isomerase activity and preparation and application | 浙江大学 | 2017-11-03 | — | — | CN | claimed |
| EP-2734541-B1 | NOVEL IL-17R-ECD MUTANTS | THE NAT INST FOR BIOTECHNOLOGY IN THE NEGEV LTD (IL) | 2017-09-06 | — | — | EP | claimed |
| CN-101969970-B | combination therapy with antibody-drug conjugates | SEATTLE GENETICS, INC. (US) | 2014-10-15 | — | — | CN | claimed |
| CN-102837341-B | Mildew-proof and mothproof treatment method for bamboo materials | UNIV CENTRAL SOUTH FORESTRY | 2014-08-13 | — | — | CN | claimed |
| US-20140135472-A1 | AFFINITY TAGS ABLE TO DETECT FRAMESHIFTS | Syndecion, LLC (US) | 2014-05-15 | — | — | US | claimed |
| CN-103597071-A | Chemosensory receptor ligand-based therapies | ELCELYX THERAPEUTICS INC | 2014-02-19 | — | — | CN | claimed |
| WO-2001080911-A1 | BREATHABLE ABSORBENT ARTICLES COMPRISING CHITOSAN MATERIAL | THE PROCTER & GAMBLE COMPANY (US) | 2001-11-01 | — | — | WO | claimed |
| WO-2001080915-A1 | ABSORBENT ARTICLES COMPRISING A CATIONIC POLYSACCHARIDE AND SILICATE | THE PROCTER & GAMBLE COMPANY (US) | 2001-11-01 | — | — | WO | claimed |
| WO-2001080912-A1 | CHITOSAN MATERIAL WITH AN ANIONIC ABSORBENT GELLING MATERIAL | THE PROCTER & GAMBLE COMPANY (US) | 2001-11-01 | — | — | WO | claimed |
| EP-1149594-A1 | Articles comprising chitosan material and an anionic absorbent gelling material | THE PROCTER & GAMBLE COMPANY (US) | 2001-10-31 | — | — | EP | claimed |
| EP-1149593-A1 | Articles comprising cationic polysaccharides and acidic pH buffering means | THE PROCTER & GAMBLE COMPANY (US) | 2001-10-31 | — | — | EP | claimed |
| EP-1149597-A1 | Breathable absorbent articles comprising chitosan material | THE PROCTER & GAMBLE COMPANY (US) | 2001-10-31 | — | — | EP | claimed |
| EP-1149596-A1 | Absorbent articles comprising a cationic polysaccharide and silicate | THE PROCTER & GAMBLE COMPANY (US) | 2001-10-31 | — | — | EP | claimed |
| EP-1149595-A1 | Odour control system comprising a cationic polysaccharide and an odour controlling agent | THE PROCTER & GAMBLE COMPANY (US) | 2001-10-31 | — | — | EP | claimed |
| EP-0139592-B1 | PROCESS AND APPARATUS FOR THE PRODUCTION OF AMINOACIDS BY FERMENTATION | LES PRODUITS ORGANIQUES DU SANTERRE ORSAN (FR) | 1992-03-25 | — | — | EP | claimed |
| EP-0374097-A2 | Use of peptide isosteres as retroviral protease inhibitors | CIBA-GEIGY AG (CH) | 1990-06-20 | — | — | EP | claimed |