Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dl-Phenylalanine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | ALPI | P09923 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | XIAP | P98170 | 1/20 | 0.59 |
| ▸ | CTSC | P53634 | 2/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 3/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.45 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine SCHEMBL148429 | 1.00 | SLC7A5 (0.59) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL498385 | 1.00 | SLC7A5 (0.59) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL22468204 | 1.00 | SLC7A5 (0.59) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine SCHEMBL28136484 | 1.00 | SLC7A5 (0.59) | SLC7A5PTGS1ALPIPKMXIAP | |
| D-Phenylalanine SCHEMBL2184336 | 1.00 | SLC7A5 (0.59) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine SCHEMBL2478802 | 1.00 | SLC7A5 (0.59) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL5134569 | 1.00 | SLC7A5 (0.59) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL21899689 | 0.95 | SLC7A5 (0.54) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine SCHEMBL4405170 | 0.95 | SLC7A5 (0.54) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL21899690 | 0.95 | SLC7A5 (0.54) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118304208-A | Use of cyclic dipeptides for skin whitening | 陕西慧康生物科技有限责任公司 | 2024-07-09 | — | — | CN | claimed |
| CN-116854772-A | Analogue of endomorphin and adenine conjugated peptide with analgesic activity and synthesis method thereof | 中国人民解放军空军军医大学 | 2023-10-10 | — | — | CN | claimed |
| CN-105331652-A | Microbial production technology of Cyclo(D-Phe-D-Pro) | UNIV GANSU AGRICULTURAL | 2016-02-17 | — | — | CN | claimed |
| CN-118304208-A | Use of cyclic dipeptides for skin whitening | 陕西慧康生物科技有限责任公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-116854772-A | Analogue of endomorphin and adenine conjugated peptide with analgesic activity and synthesis method thereof | 中国人民解放军空军军医大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-105331652-A | Microbial production technology of Cyclo(D-Phe-D-Pro) | UNIV GANSU AGRICULTURAL | 2016-02-17 | — | — | CN | disclosed |
| EP-2373674-A1 | 2-(N-SUBSTITUTED PIPERAZINYL) STEROID DERIVATIVES | Université Laval (CA) | 2011-10-12 | — | — | EP | disclosed |
| CN-101951931-A | Immunomodulating compositions and uses therefor | OPAL THERAPEUTICS PTY LTD | 2011-01-19 | — | — | CN | disclosed |
| WO-2010060215-A1 | 2-(N-SUBSTITUTED PIPERAZINYL) STEROID DERIVATIVES | UNIVERSITé LAVAL (CA) | 2010-06-03 | — | — | WO | disclosed |
| CN-101684148-A | Novel surface protein of neisseria meningitidis | UNIV QUEENSLAND | 2010-03-31 | — | — | CN | disclosed |
| CN-101198353-A | Immunomodulatory compositions and uses thereof | UNIV QUEENSLAND (AU) | 2008-06-11 | — | — | CN | disclosed |
| CN-1835967-A | Viral polymerase and modulation thereof | MELBOURNE HEALTH (AU) | 2006-09-20 | — | — | CN | disclosed |
| CN-1832960-A | Immunomodulating compositions, uses therefor and processes for their production | UNIV MELBOURNE (AU) | 2006-09-13 | — | — | CN | disclosed |
| CN-1802432-A | Insect chymotrypsin and inhibitors thereof | HEXIMA LTD (AU) | 2006-07-12 | — | — | CN | disclosed |
| CN-1791675-A | Viral vectors expressing fusion of viral large envelope protein and protein of interest | HEPGENICS PTY LTD (AU) | 2006-06-21 | — | — | CN | disclosed |
| CN-1247613-C | Novel omega-conotoxin peptides | UNIV QUEENSLAND (AU) | 2006-03-29 | — | — | CN | disclosed |
| CN-1223682-C | Diagnostic test | GOVERNMENT OF SINGAPORE (SG) | 2005-10-19 | — | — | CN | disclosed |
| CN-1680592-A | Diagnostic test | REPUBLIC OF SINGAPORE (SG) | 2005-10-12 | — | — | CN | disclosed |
| CN-1468311-A | Isomaltulose synthase | ��ʿ����ѧ | 2004-01-14 | — | — | CN | disclosed |
| CN-1284965-A | Novel surface proteins of neisseria meningitidis | UNIV QUEENSLAND (AU) | 2001-02-21 | — | — | CN | disclosed |