⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20364497 | 0.80 | — | — | |
| SCHEMBL9069700 | 0.79 | TSHR (0.30) | — | |
| SCHEMBL3801880 | 0.76 | — | — | |
| SCHEMBL14282537 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL4069273 | 0.74 | — | — | |
| Methyl Alcohol SCHEMBL28753392 | 0.74 | LMNA (0.38) | — | |
| SCHEMBL15702979 | 0.74 | — | — | |
| SCHEMBL37352 | 0.72 | LMNA (0.40) | — | |
| SCHEMBL3674117 | 0.72 | TSHR (0.33) | — | |
| SCHEMBL3669234 | 0.72 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170267703-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-09-21 | — | — | US | disclosed |
| US-9751901-B2 | Method for preparing a polyorganosiloxane and a polyorganosiloxane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-09-05 | — | — | US | disclosed |
| US-20170088566-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-03-30 | — | — | US | disclosed |
| US-20160159827-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SHINETSU CHEMICAL CO (JP) | 2016-06-09 | — | — | US | disclosed |
| US-9340649-B2 | Method for preparing a polyorganosiloxane and a polyorganosiloxane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-05-17 | — | — | US | disclosed |
| US-20150299397-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SHINETSU CHEMICAL CO (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20140213809-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-07-31 | — | — | US | disclosed |