Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71182 | 0.80 | TTR (0.65) | ALDH1A1TTRBACE1CYP3A4CHRM1 | |
| SCHEMBL23907108 | 0.77 | TTR (0.52) | ALDH1A1TTRBACE1CYP3A4CHRM1 | |
| SCHEMBL7875531 | 0.75 | CYP3A4 (0.46) | ALDH1A1TTRBACE1CYP3A4CHRM1 | |
| SCHEMBL1655127 | 0.73 | BACE1 (0.47) | ALDH1A1TTRBACE1CYP3A4CHRM1 | |
| SCHEMBL18388076 | 0.73 | ACHE (0.40) | ALDH1A1TTRACHE | |
| SCHEMBL2261818 | 0.73 | TTR (0.56) | TTRGABRA1GABRB2 | |
| SCHEMBL16532790 | 0.71 | CYP3A4 (0.42) | ALDH1A1TTRBACE1CYP3A4CHRM1 | |
| SCHEMBL13099334 | 0.69 | CHEK1 (0.64) | ALDH1A1TTRCYP3A4ALOX15ALB | |
| SCHEMBL13096681 | 0.69 | CHEK1 (0.48) | ALDH1A1TTRCYP3A4ALOX15ALB | |
| SCHEMBL2321509 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140212575-A1 | Novel Self-Assembling Nanocomposite Structures and Methods of Preparing Same | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140212575-A1 | Novel Self-Assembling Nanocomposite Structures and Methods of Preparing Same | CACYBP, CAPG, NCBP2 | ALDH1A1 2357/4885TTR 1251/4885BACE1 4130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.