Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 19/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1590292 | 0.96 | PTGER4 (0.57) | PTGER4HTR1AADRA1A | |
| SCHEMBL3563601 | 0.87 | PTGER4 (0.70) | PTGER4HTR1AADRA1A | |
| SCHEMBL1589886 | 0.84 | PTGER4 (0.75) | PTGER4 | |
| SCHEMBL1590136 | 0.84 | PTGER4 (0.55) | PTGER4HTR1AADRA1A | |
| SCHEMBL3561366 | 0.83 | PTGER4 (0.73) | PTGER4HTR1AADRA1A | |
| SCHEMBL3569685 | 0.82 | PTGER4 (0.71) | PTGER4HTR1AADRA1A | |
| SCHEMBL3566808 | 0.82 | PTGER4 (0.62) | PTGER4HTR1AADRA1A | |
| SCHEMBL3564981 | 0.81 | PTGER4 (0.73) | PTGER4HTR1AADRA1A | |
| SCHEMBL3567447 | 0.81 | PTGER4 (0.71) | PTGER4HTR1AADRA1A | |
| SCHEMBL10058572 | 0.81 | PTGER4 (0.59) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092561-A1 | BENZOISOINDOLE DERIVATIVES FOR THE TREATMENT OF PAIN | GLAXO GROUP LIMITED (GB) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092561-A1 | BENZOISOINDOLE DERIVATIVES FOR THE TREATMENT OF PAIN | OPRK1, OPRD1, OPRL1 | PTGER4 106/4885HTR1A 49/4885ADRA1A 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.