Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.65 |
| ▸ | DRD4 | P21917 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.56 |
| ▸ | PDE5A | O76074 | 1/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3238921 | 0.99 | BCHE (0.66) | BCHEDRD4SIGMAR1ACHEFAAH | |
| SCHEMBL27858398 | 0.84 | BCHE (0.66) | BCHEDRD4SIGMAR1ACHEFAAH | |
| SCHEMBL27493904 | 0.83 | ALDH1A1 (0.43) | BCHEPDE4DDRD2KDM4ENPC1 | |
| SCHEMBL27608094 | 0.82 | MEN1 (0.69) | DRD4SIGMAR1ACHEFAAHDRD2 | |
| SCHEMBL29550512 | 0.79 | BCHE (1.00) | BCHEDRD4SIGMAR1ACHEFAAH | |
| SCHEMBL13605247 | 0.79 | BCHE (1.00) | BCHEDRD4SIGMAR1ACHEFAAH | |
| SCHEMBL28409804 | 0.78 | BCHE (0.67) | BCHEDRD4SIGMAR1ACHEFAAH | |
| SCHEMBL16291177 | 0.78 | MEN1 (0.68) | SIGMAR1ACHEFAAHCHRM2 | |
| SCHEMBL2794872 | 0.75 | ALDH1A1 (0.63) | SIGMAR1KDM4E | |
| SCHEMBL1475064 | 0.75 | SIGMAR1 (0.71) | DRD4SIGMAR1DRD2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2948429-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | INSA (Institut National des Sciences Appliquees) de Rouen (FR) | 2015-12-02 | — | — | EP | disclosed |
| WO-2014114742-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | INSA (INSTITUT NATIONAL DES SCIENCES APPLIQUÉES) DE ROUEN (FR) | 2014-07-31 | — | — | WO | disclosed |