Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL5425946 | 0.90 | ALDH1A1 (0.50) | ALDH1A1EPHX1CES2CES1HSD11B1 | |
| Biphenyl SCHEMBL688111 | 0.88 | ALDH1A1 (0.47) | ALDH1A1EPHX1CES2CES1HSD11B1 | |
| Biphenyl SCHEMBL8438932 | 0.87 | ALDH1A1 (0.40) | ALDH1A1EPHX1CES2CES1HSD11B1 | |
| Biphenyl SCHEMBL10768512 | 0.83 | ALDH1A1 (0.42) | ALDH1A1EPHX1CES2CES1HSD11B1 | |
| Bicarbonate SCHEMBL7025736 | 0.83 | ALDH1A1 (0.57) | ALDH1A1EPHX1CES2CES1HSD11B1 | |
| Biphenyl SCHEMBL2169497 | 0.83 | ALDH1A1 (0.57) | ALDH1A1EPHX1CES2CES1HSD11B1 | |
| Bicarbonate SCHEMBL10775900 | 0.83 | ALDH1A1 (0.57) | ALDH1A1EPHX1CES2CES1HSD11B1 | |
| Bicarbonate SCHEMBL10581815 | 0.83 | ALDH1A1 (0.57) | ALDH1A1EPHX1CES2CES1HSD11B1 | |
| SCHEMBL10784791 | 0.80 | ALDH1A1 (0.53) | ALDH1A1EPHX1CES2CES1HSD11B1 | |
| Biphenyl SCHEMBL8588399 | 0.80 | ALDH1A1 (0.53) | ALDH1A1EPHX1HSD11B1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2717 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073336-A | Preparation method of sulfhydryl alanyl amino acid ester salt of peramivir | 江西中医药大学 | 2022-09-20 | — | — | CN | claimed |
| EP-3986135-A1 | PLANT TREATMENT COMPOSITION | Croda International PLC (GB) | 2022-04-27 | — | — | EP | claimed |
| WO-2021236653-A1 | REAL TIME BREATH ANALYZER FOR DETECTING VOLATILE ORGANIC COMPOUNDS AND IDENTIFYING DISEASES OR DISORDERS | CANARY HEALTH TECHNOLOGIES INC. (US) | 2021-11-25 | — | — | WO | claimed |
| US-11045111-B1 | Real time breath analyzer for detecting volatile organic compounds and identifying diseases or disorders | CANARY HEALTH TECHNOLOGIES INC. (US) | 2021-06-29 | — | — | US | claimed |
| WO-2020254104-A1 | PLANT TREATMENT COMPOSITION | CRODA INTERNATIONAL PLC (GB) | 2020-12-24 | — | — | WO | claimed |
| US-8450518-B2 | Method for preparing a carbamate, a catalyst applied in the method, a method for preparing the catalyst and use thereof | BAYER MATERIALSCIENCE AG (DE) | 2013-05-28 | — | — | US | claimed |
| CN-102775329-A | Preparation method of carbodiimide | JINAN SHENGQUANTANG HETANG BIO TECHNOLOGY CO LTD | 2012-11-14 | — | — | CN | claimed |
| CN-102408355-A | Synthetic method of dicyclohexylcarbodiimide compound | UNIV ZHEJIANG TECHNOLOGY | 2012-04-11 | — | — | CN | claimed |
| WO-2011151701-A1 | 6 - METHYL - 4 - PHENYL - 5 - ( PHENYL OR CYCLOALKYL) CARBAMOYL - 1,2,3, 4 - TETRAHYDROPYRIMIDIN- 2 - ONE DERIVATIVES AS ANTITUBERCULAR AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-12-08 | — | — | WO | claimed |
| US-20100274041-A1 | METHOD FOR PREPARING A CARBAMATE, A CATALYST APPLIED IN THE METHOD, A METHOD FOR PREPARING THE CATALYST AND USE THEREOF | BAYER MATERIALSCIENCE AG (DE) | 2010-10-28 | — | — | US | claimed |
| US-20060178422-A1 | Process for making (2S, 3aS, 7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl) butyl] amino]-1-oxopropyl] octahydro-1H-indole-2-carboxylic acid | IPCA LABORATORIES, LTD. (IN) | 2006-08-10 | — | — | US | claimed |
| WO-2006051506-A2 | CONVENIENT SYNTHESIS OF 1 --> 3 C-BRANCHED DENDRONS | THE UNIVERSITY OF AKRON (US) | 2006-05-18 | — | — | WO | claimed |
| US-20050222450-A1 | Process for preparing carbamates | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-10-06 | — | — | US | claimed |
| CN-1220686-C | Beta-hydroxy-alpha-amino acid and its derivatives and synthesizing method for preparing template | LANZHOU UNVI (CN) | 2005-09-28 | — | — | CN | claimed |
| WO-2005063698-A1 | PROCESS FOR PREPARING CARBAMATES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-07-14 | — | — | WO | claimed |
| CN-1528754-A | Beta-hydroxy-alpha-amino acid and its derivatives and synthesizing method for preparing template | 兰州大学 | 2004-09-15 | — | — | CN | claimed |
| US-5550259-A | DICITRATE CYCLIC DIESTER CAN BE USED TO PREVENT OR REDUCE THE EFFECTS OF CALCIFICATION-RELATED DISEASE | THE UNIVERSITY OF FLORIDA (US) | 1996-08-27 | — | — | US | claimed |
| EP-0704057-A1 | NOVEL CLINICAL MARKER AND THERAPEUTIC AGENT IN KIDNEY STONE DISEASE AND METHODS OF USE | UNIVERSITY OF FLORIDA (US) | 1996-04-03 | — | — | EP | claimed |
| WO-1995000844-A1 | NOVEL CLINICAL MARKER AND THERAPEUTIC AGENT IN KIDNEY STONE DISEASE AND METHODS OF USE | UNIVERSITY OF FLORIDA (US) | 1995-01-05 | — | — | WO | claimed |
| US-4363920-A | Process for the preparation of N-[2-(-thenoyl)thiopropionyl]-glycine | B.T.B. INDUSTRIA CHIMICA S.P.A. (IT) | 1982-12-14 | — | — | US | claimed |