Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL159042 | 0.88 | ALDH1A1 (0.53) | ALDH1A1EPHX1CES2CES1HSD11B1 | |
| SCHEMBL10784791 | 0.88 | ALDH1A1 (0.53) | ALDH1A1EPHX1CES2CES1HSD11B1 | |
| Urea SCHEMBL28033583 | 0.88 | ALDH1A1 (0.53) | ALDH1A1EPHX1CES2CES1HSD11B1 | |
| Biphenyl SCHEMBL5425946 | 0.85 | ALDH1A1 (0.50) | ALDH1A1EPHX1CES2CES1HSD11B1 | |
| Urea SCHEMBL28033577 | 0.84 | ALDH1A1 (0.57) | ALDH1A1EPHX1CES2CES1HSD11B1 | |
| Biphenyl SCHEMBL2145778 | 0.82 | ALDH1A1 (0.47) | ALDH1A1EPHX1CES2CES1HSD11B1 | |
| Carbamic Acid SCHEMBL27547174 | 0.81 | ALDH1A1 (0.53) | ALDH1A1EPHX1CES2CES1HSD11B1 | |
| Cyclohexane SCHEMBL10908944 | 0.80 | LMNA (0.42) | ALDH1A1EPHX1CES2CES1ALOX5 | |
| Acetamide SCHEMBL28324196 | 0.79 | ALDH1A1 (0.50) | ALDH1A1EPHX1CES2CES1HSD11B1 | |
| Biphenyl SCHEMBL10768512 | 0.78 | ALDH1A1 (0.42) | ALDH1A1EPHX1CES2CES1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021141002-A1 | (METH)ACRYLIC ACID ESTER COMPOUND HAVING ISOCYANATE GROUP, AND METHOD FOR PRODUCING SAME | 昭和電工株式会社 | 2021-07-15 | — | — | WO | claimed |
| WO-2021141002-A1 | (METH)ACRYLIC ACID ESTER COMPOUND HAVING ISOCYANATE GROUP, AND METHOD FOR PRODUCING SAME | 昭和電工株式会社 | 2021-07-15 | — | — | WO | disclosed |
| EP-1904438-B1 | DICYCLOALKYLCARBAMOYL UREAS AS GLUCOKINASE ACTIVATORS | NOVO NORDISK AS (DK) | 2012-02-29 | — | — | EP | disclosed |
| US-7999114-B2 | Dicycloalkylcarbamoyl ureas as glucokinase activators | NOVO NORDISK A/S (DK) | 2011-08-16 | — | — | US | disclosed |
| US-20080319028-A1 | Dicycloalkylcarbamoyl Ureas As Glucokinase Activators | NOVO NORDISK A/S (DK) | 2008-12-25 | — | — | US | disclosed |
| EP-1904438-A1 | DICYCLOALKYLCARBAMOYL UREAS AS GLUCOKINASE ACTIVATORS | Novo Nordisk A/S (DK) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007006761-A1 | DICYCLOALKYLCARBAMOYL UREAS AS GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |
| US-4770820-A | Process for the preparation of carbamoyl chlorides derived from secondary amines | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319028-A1 | Dicycloalkylcarbamoyl Ureas As Glucokinase Activators | GCK, HK1, GCKR | ALDH1A1 2374/4885EPHX1 4231/4885CES2 600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.