Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15904353 | 0.80 | BHMT (0.33) | BHMTALDH1A1SLC22A6 | |
| SCHEMBL26234866 | 0.76 | BHMT (0.41) | BHMTALDH1A1SLC22A6 | |
| SCHEMBL270439 | 0.75 | — | — | |
| SCHEMBL9974590 | 0.73 | BHMT (0.52) | BHMTSLC22A6 | |
| SCHEMBL270952 | 0.72 | — | — | |
| SCHEMBL15903930 | 0.71 | SLC22A6 (0.35) | ALDH1A1SLC22A6 | |
| SCHEMBL1712694 | 0.70 | — | — | |
| SCHEMBL425046 | 0.69 | BHMT (0.48) | BHMTSLC22A6 | |
| SCHEMBL14360558 | 0.69 | BHMT (0.48) | BHMTSLC22A6 | |
| SCHEMBL15904350 | 0.69 | GABRP (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2948450-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Viamet Pharmaceuticals, Inc. (US) | 2015-12-02 | — | — | EP | disclosed |
| WO-2014117090-A1 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2014-07-31 | — | — | WO | disclosed |