Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF20A | O95235 | 10/20 | 0.82 |
| ▸ | NPC1 | O15118 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.62 |
| ▸ | CLK1 | P49759 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15904684 | 1.00 | KIF20A (0.82) | KIF20ANPC1MEN1KMT2ADYRK1A | |
| SCHEMBL2724567 | 0.90 | KIF20A (1.00) | KIF20ANPC1MEN1KMT2ADYRK1A | |
| SCHEMBL2724561 | 0.90 | KIF20A (1.00) | KIF20ANPC1MEN1KMT2ADYRK1A | |
| SCHEMBL19193662 | 0.87 | KIF20A (0.89) | KIF20ANPC1MEN1KMT2ADYRK1A | |
| SCHEMBL19192415 | 0.85 | KIF20A (0.75) | KIF20ANPC1MEN1KMT2ADYRK1A | |
| SCHEMBL8831354 | 0.83 | MEN1 (0.72) | KIF20ANPC1MEN1KMT2ADYRK1A | |
| SCHEMBL8831355 | 0.83 | MEN1 (0.72) | KIF20ANPC1MEN1KMT2ADYRK1A | |
| SCHEMBL14964098 | 0.83 | KIF20A (0.81) | KIF20ANPC1MEN1KMT2ADYRK1A | |
| SCHEMBL2725696 | 0.82 | KIF20A (0.69) | KIF20ANPC1MEN1KMT2ADYRK1A | |
| SCHEMBL2727191 | 0.82 | KIF20A (0.69) | KIF20ANPC1MEN1KMT2ADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014115071-A1 | KINASE INHIBITORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-31 | — | — | WO | disclosed |
| WO-2014115071-A1 | KINASE INHIBITORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-31 | — | — | WO | disclosed |