Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | LATS1 | O95835 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15905000 | 0.92 | ALDH1A1 (0.39) | MAPTALDH1A1GAALMNAP4HB | |
| SCHEMBL15905132 | 0.92 | TACR3 (0.37) | MAPTALDH1A1GAALMNAP4HB | |
| SCHEMBL15905453 | 0.91 | GAA (0.35) | MAPTALDH1A1GAALMNAP4HB | |
| SCHEMBL15905560 | 0.87 | ALDH1A1 (0.33) | MAPTALDH1A1GAALMNAP4HB | |
| SCHEMBL18879087 | 0.85 | MAPT (0.35) | MAPTALDH1A1GAALMNAP4HB | |
| SCHEMBL15905436 | 0.84 | TACR3 (0.36) | ALDH1A1GAALMNATACR3CYP3A4 | |
| SCHEMBL15905087 | 0.83 | LATS1 (0.34) | MAPTALDH1A1GAALMNAP4HB | |
| SCHEMBL15905467 | 0.83 | GAA (0.36) | MAPTALDH1A1GAALMNAP4HB | |
| SCHEMBL15919401 | 0.82 | TACR3 (0.38) | MAPTALDH1A1GAALMNAP4HB | |
| SCHEMBL18879088 | 0.79 | ALDH1A1 (0.34) | MAPTALDH1A1GAALMNAP4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663488-B2 | Metalloenzyme inhibitor compounds | VIAMET PHARMACEUTICALS, INC. (US) | 2017-05-30 | — | — | US | claimed |
| EP-2948450-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Viamet Pharmaceuticals, Inc. (US) | 2015-12-02 | — | — | EP | claimed |
| WO-2014117090-A1 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2014-07-31 | — | — | WO | claimed |
| EP-2948450-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Viamet Pharmaceuticals, Inc. (US) | 2015-12-02 | — | — | EP | disclosed |
| WO-2014117090-A1 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2014-07-31 | — | — | WO | disclosed |