Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 6/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TACR2 | P21452 | 2/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15905497 | 0.85 | MAPT (0.35) | MAPTGAALMNAALDH1A1P4HB | |
| SCHEMBL15905560 | 0.84 | ALDH1A1 (0.33) | MAPTGAALMNAALDH1A1P4HB | |
| SCHEMBL15919298 | 0.84 | TACR3 (0.36) | MAPTGAALMNAALDH1A1P4HB | |
| Hydrochloric Acid SCHEMBL17313841 | 0.83 | TACR3 (0.35) | MAPTGAALMNAALDH1A1P4HB | |
| SCHEMBL15905132 | 0.83 | TACR3 (0.37) | MAPTGAALMNAALDH1A1P4HB | |
| SCHEMBL15919652 | 0.82 | LMNA (0.36) | MAPTGAALMNAALDH1A1P4HB | |
| Hydrochloric Acid SCHEMBL17313777 | 0.81 | LMNA (0.36) | MAPTGAALMNAALDH1A1P4HB | |
| SCHEMBL15919401 | 0.79 | TACR3 (0.38) | MAPTGAALMNAALDH1A1P4HB | |
| SCHEMBL17327500 | 0.78 | TACR3 (0.34) | MAPTGAAALDH1A1TACR3TP53 | |
| SCHEMBL15905000 | 0.78 | ALDH1A1 (0.39) | MAPTGAALMNAALDH1A1P4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663488-B2 | Metalloenzyme inhibitor compounds | VIAMET PHARMACEUTICALS, INC. (US) | 2017-05-30 | — | — | US | claimed |