Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 12/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10089983 | 0.93 | ELANE (0.39) | ELANEGLASMN1; SMN2DGAT2LMNA | |
| SCHEMBL13085376 | 0.93 | CNR1 (0.37) | ELANE | |
| SCHEMBL317728 | 0.92 | ELANE (0.37) | ELANEGLASMN1; SMN2DGAT2LMNA | |
| SCHEMBL10089947 | 0.91 | CNR1 (0.38) | — | |
| SCHEMBL10089920 | 0.91 | SMN1; SMN2 (0.36) | GLASMN1; SMN2DGAT2LMNA | |
| SCHEMBL10089919 | 0.91 | ELANE (0.36) | ELANE | |
| SCHEMBL10089889 | 0.90 | CNR1 (0.34) | — | |
| SCHEMBL10089843 | 0.90 | RORC (0.39) | ELANE | |
| SCHEMBL10089952 | 0.90 | SLC2A1 (0.34) | — | |
| SCHEMBL10089988 | 0.89 | MAPK14 (0.33) | DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791143-B2 | Anthranilic diamide derivatives having cyclic side-chains | BAYER CROPSCIENCE AG (DE) | 2014-07-29 | — | — | US | disclosed |