SCHEMBL10089952

SCHEMBL10089952

Cc1cc(C#N)cc(C(=O)NC2CSC2)c1NC(=O)c1cc(Cn2nnc(C(F)(F)F)n2)nn1-c1ccccc1Cl

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 10/20 0.34
SLC2A3 P11169 10/20 0.34
SLC2A4 P14672 10/20 0.34
SLC2A2 P11168 3/20 0.32
CNR1 P21554 5/20 0.32
CETP P11597 1/20 0.31
RORC P51449 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085376 0.94 CNR1 (0.37) SLC2A1SLC2A3SLC2A4CNR1RORC
SCHEMBL10089889 0.94 CNR1 (0.34) SLC2A1SLC2A3SLC2A4CNR1RORC
SCHEMBL10089947 0.93 CNR1 (0.38) SLC2A1SLC2A3SLC2A4CNR1RORC
SCHEMBL10089843 0.92 RORC (0.39) SLC2A1SLC2A3SLC2A4SLC2A2CNR1
SCHEMBL10089919 0.91 ELANE (0.36) CNR1RORC
SCHEMBL10089865 0.91 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2RORC
SCHEMBL15905591 0.90 ELANE (0.38)
SCHEMBL10083881 0.90 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2CNR1
SCHEMBL13085547 0.88 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2CNR1
SCHEMBL10076311 0.88 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8791143-B2 Anthranilic diamide derivatives having cyclic side-chains BAYER CROPSCIENCE AG (DE) 2014-07-29 US disclosed
US-20120010249-A1 Anthranilic diamide derivatives having cyclic side-chains BAYER CROPSCIENCE AG (DE) 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010249-A1 Anthranilic diamide derivatives having cyclic side-chains DDT, ADCY1, ANTXR2 SLC2A1 3782/4885SLC2A3 3762/4885SLC2A4 3927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.