Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972548 | 0.77 | PLA2G7 (0.32) | — | |
| SCHEMBL1160312 | 0.73 | CYP3A4 (0.33) | CYP3A4CA1CA9ALDH1A1KDM1A | |
| SCHEMBL21616443 | 0.71 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL10974043 | 0.68 | NPC1 (0.46) | KMT2ACYP19A1 | |
| SCHEMBL22210998 | 0.67 | HTR2A (0.31) | — | |
| SCHEMBL13867728 | 0.66 | HSP90AA1 (0.41) | — | |
| SCHEMBL10703271 | 0.64 | NFKB1 (0.33) | MAOA | |
| SCHEMBL18950023 | 0.63 | — | — | |
| SCHEMBL7888051 | 0.63 | — | — | |
| SCHEMBL13845754 | 0.63 | NPC1 (0.37) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791303-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-07-29 | — | — | US | disclosed |