Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717147 | 0.81 | KMT2A (0.60) | KMT2AALDH1A1MAPTMEN1GPR139 | |
| SCHEMBL27845658 | 0.80 | ALDH1A1 (0.78) | KMT2AALDH1A1MAPTMEN1CYP1A2 | |
| SCHEMBL27827039 | 0.79 | MAPT (0.72) | KMT2AALDH1A1MAPTMEN1LMNA | |
| SCHEMBL2984329 | 0.79 | KMT2A (0.60) | KMT2AALDH1A1MEN1GPR139ATM | |
| SCHEMBL13331944 | 0.77 | PARP1 (0.58) | KMT2AALDH1A1MEN1GPR139ATM | |
| SCHEMBL8858800 | 0.76 | KMT2A (0.61) | KMT2AALDH1A1MAPTMEN1GPR139 | |
| SCHEMBL23014097 | 0.75 | MEN1 (0.65) | KMT2AALDH1A1MAPTMEN1GPR139 | |
| SCHEMBL10064202 | 0.75 | MEN1 (0.65) | KMT2AALDH1A1MEN1GPR139ATM | |
| SCHEMBL10004955 | 0.74 | KMT2A (0.62) | KMT2AALDH1A1MAPTMEN1GPR139 | |
| SCHEMBL3815582 | 0.73 | P2RX7 (0.55) | KMT2AALDH1A1MEN1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791299-B2 | Compounds for the inhibition of herpes viruses | UNIVERSITE LAVAL (CA) | 2014-07-29 | — | — | US | disclosed |