SCHEMBL15906279

SCHEMBL15906279

C=C(C)C(=O)CCc1ccc(-c2ccc(OC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.47
KMT2A Q03164 4/20 0.43
ATM Q13315 1/20 0.43
THRB P10828 2/20 0.41
FFAR1 O14842 4/20 0.40
F2RL1 P55085 1/20 0.40
MEN1 O00255 1/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
PLAAT3 P53816 1/20 0.37
PLAAT5 Q96KN8 1/20 0.37
PLAAT2 Q9NWW9 1/20 0.37
PLAAT4 Q9UL19 1/20 0.37
HSD17B10 Q99714 1/20 0.37
LMNA P02545 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
TP53 P04637 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26362357 0.89 ELANE (0.53) ELANEKMT2AATMTHRBFFAR1
SCHEMBL26362231 0.89 ELANE (0.53) ELANEKMT2AATMTHRBFFAR1
SCHEMBL17433325 0.88 KMT2A (0.54) ELANEKMT2AATMTHRBFFAR1
SCHEMBL16559867 0.85 ELANE (0.49) ELANEKMT2AATMTHRBMEN1
SCHEMBL883697 0.85 THRB (0.58) ELANEKMT2AATMTHRBNPC1
SCHEMBL20827825 0.85 THRB (0.58) ELANEKMT2AATMTHRBNPC1
SCHEMBL17484464 0.85 ELANE (0.49) ELANEKMT2AATMTHRBMEN1
SCHEMBL15468765 0.85 FFAR1 (0.42) ELANEFFAR1
SCHEMBL26235681 0.84 ELANE (0.51) ELANEKMT2AATMTHRBFFAR1
SCHEMBL17791332 0.84 ELANE (0.57) ELANEKMT2AATMTHRBF2RL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160244669-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2016-08-25 US disclosed
US-20160230093-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2016-08-11 US disclosed
EP-2759869-B1 LCD DEVICE DAINIPPON INK & CHEMICALS (JP) 2016-06-08 EP disclosed
EP-2759869-A1 LCD DEVICE DIC Corporation (JP) 2014-07-30 EP disclosed