Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2212092 | 0.85 | CYP19A1 (0.59) | PTGS2CYP19A1CYP11B2ESR1ESR2 | |
| SCHEMBL14922794 | 0.80 | PTGS2 (0.51) | PTGS2CYP19A1CYP11B2ESR1ESR2 | |
| SCHEMBL28143022 | 0.80 | CYP19A1 (0.53) | PTGS2CYP19A1CYP11B2ESR1ESR2 | |
| SCHEMBL2786938 | 0.79 | ESR1 (0.64) | PTGS2CYP19A1CYP11B2ESR1ESR2 | |
| SCHEMBL5338783 | 0.79 | ESR1 (0.64) | PTGS2CYP19A1CYP11B2ESR1ESR2 | |
| SCHEMBL204220 | 0.79 | ESR1 (0.60) | CYP19A1ESR1ESR2MAOAMAOB | |
| SCHEMBL29195200 | 0.79 | PTGS2 (0.63) | PTGS2CYP19A1CYP11B2ESR1ESR2 | |
| SCHEMBL26867242 | 0.79 | PTGS2 (0.63) | PTGS2CYP19A1CYP11B2ESR1ESR2 | |
| SCHEMBL28816911 | 0.78 | KIF11 (0.54) | PTGS2CYP19A1CYP11B2ESR1ESR2 | |
| SCHEMBL28816910 | 0.78 | KIF11 (0.54) | PTGS2CYP19A1CYP11B2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2759530-A1 | Triphenylamine derivative, and charge transport material and electrophotographic photoreceptor using the same | Takasago International Corporation (JP) | 2014-07-30 | — | — | EP | disclosed |