Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 12/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959210 | 0.88 | ALDH1A1 (0.67) | CCR9ALDH1A1KDM4EGLAGAA | |
| SCHEMBL307185 | 0.86 | CCR9 (0.74) | CCR9ALDH1A1MAPTLMNA | |
| SCHEMBL31384417 | 0.85 | MAPT (0.67) | ALDH1A1KDM4EGLAGAAMAPT | |
| SCHEMBL333291 | 0.85 | MAPT (0.67) | ALDH1A1KDM4EGLAGAAMAPT | |
| SCHEMBL28650 | 0.84 | CCR9 (0.56) | CCR9ALDH1A1MAPTSMN1; SMN2LMNA | |
| Ammonia Solution, Strong SCHEMBL28210514 | 0.84 | MAPT (0.65) | ALDH1A1KDM4EGLAGAAMAPT | |
| Ethane SCHEMBL11534058 | 0.84 | MAPT (0.65) | ALDH1A1KDM4EGLAGAAMAPT | |
| SCHEMBL15906617 | 0.83 | ALDH1A1 (0.56) | CCR9ALDH1A1KDM4EGLAGAA | |
| SCHEMBL19860936 | 0.83 | CCR9 (0.54) | CCR9ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL15906606 | 0.82 | CCR9 (0.66) | CCR9ALDH1A1KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798223-B2 | Aryl sulfonamides | CHEMOCENTRYX INC (US) | 2014-07-30 | — | — | EP | disclosed |