Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31384417 | 0.98 | MAPT (0.67) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL333291 | 0.98 | MAPT (0.67) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| Ethane SCHEMBL11534058 | 0.97 | MAPT (0.65) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| Glycine SCHEMBL11600509 | 0.90 | SMN1; SMN2 (0.58) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL8959210 | 0.88 | ALDH1A1 (0.67) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL11827090 | 0.84 | MAPT (0.72) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL31000396 | 0.84 | MAPT (0.72) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL15906641 | 0.84 | CCR9 (0.64) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL10800720 | 0.83 | MAPT (0.64) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL11636235 | 0.83 | SMN1; SMN2 (0.64) | MAPTALDH1A1LMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107935871-A | A kind of preparation method of diazepam intermediate | 华中药业股份有限公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-107935870-A | A kind of synthetic method of 2 methylamino, 5 chlorobenzophenone | 华中药业股份有限公司 | 2018-04-20 | — | — | CN | disclosed |