SCHEMBL15907907

SCHEMBL15907907

O=C(O)CCOCOCCS

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 5/20 0.42
ACE P12821 1/20 0.41
LMNA P02545 2/20 0.36
ALKBH5 Q6P6C2 1/20 0.36
SUCNR1 Q9BXA5 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
ENPEP Q07075 5/20 0.35
ANPEP P15144 3/20 0.35
GSTK1 Q9Y2Q3 2/20 0.34
TSHR P16473 1/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6366305 0.90
SCHEMBL12092215 0.88 FOLH1 (0.44) FOLH1ACELMNAALKBH5SUCNR1
SCHEMBL40095 0.88 FOLH1 (0.44) FOLH1ACELMNAALKBH5SUCNR1
SCHEMBL13907082 0.88 FOLH1 (0.44) FOLH1ACELMNAALKBH5SUCNR1
SCHEMBL30505307 0.88 FOLH1 (0.44) FOLH1ACELMNAALKBH5SUCNR1
SCHEMBL39838 0.88 FOLH1 (0.44) FOLH1ACELMNAALKBH5SUCNR1
SCHEMBL18470513 0.87 LMNA (0.47) LMNAALKBH5SUCNR1EGLN1TSHR
SCHEMBL2263857 0.82 LMNA (0.42) LMNAALKBH5SUCNR1EGLN1TSHR
Mercaptopropionic Acid SCHEMBL331255 0.80 ACE (0.50) FOLH1ACELMNAALKBH5SUCNR1
SCHEMBL4166052 0.78 TSHR (0.43) LMNAALKBH5SUCNR1EGLN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140213641-A1 POLYMERIC NANOPARTICLES FOR DRUG DELIVERY INSTITUT QUIMIC DE SARRIA (ES) 2014-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140213641-A1 POLYMERIC NANOPARTICLES FOR DRUG DELIVERY CD44, MKI67, CD63 FOLH1 1141/4885ACE 4232/4885LMNA 469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.