Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 0.88 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144013 | 0.94 | ELANE (1.00) | ELANEALDH1A1SRD5A2KMT2AMEN1 | |
| SCHEMBL15908309 | 0.94 | ELANE (0.76) | ELANELMNAALDH1A1SRD5A2KMT2A | |
| Butanedione SCHEMBL28306363 | 0.91 | ELANE (0.94) | ELANELMNAALDH1A1SRD5A2KMT2A | |
| SCHEMBL23064191 | 0.89 | ELANE (0.91) | ELANEALDH1A1SRD5A2KMT2AMEN1 | |
| SCHEMBL15064112 | 0.87 | ELANE (0.86) | ELANELMNAKMT2AMEN1ATM | |
| SCHEMBL8671433 | 0.86 | ELANE (0.85) | ELANELMNAKMT2AMEN1POLB | |
| SCHEMBL18541651 | 0.85 | ELANE (0.73) | ELANELMNAKMT2AMEN1POLB | |
| SCHEMBL146180 | 0.85 | LMNA (0.63) | ELANELMNAALDH1A1KMT2AL3MBTL1 | |
| Benzoic Acid SCHEMBL22609156 | 0.84 | ELANE (0.81) | ELANELMNASRD5A2CES2CES1 | |
| SCHEMBL15071409 | 0.84 | ELANE (0.81) | ELANECES2CES1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226807-B1 | DENTAL CURABLE COMPOSITION | TOKUYAMA CORP (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-6933327-B2 | Dental curable composition | TOKUYAMA CORPORATION (JP) | 2005-08-23 | — | — | US | disclosed |
| US-20030036582-A1 | Dental curable composition | TOKUYAMA CORPORATION (JP) | 2003-02-20 | — | — | US | disclosed |
| EP-1226807-A1 | DENTAL CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2002-07-31 | — | — | EP | disclosed |