Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MGLL | Q99685 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14495188 | 0.89 | BCL9 (0.59) | BCL9CTNNB1GAAMGLLALDH1A1 | |
| SCHEMBL4941164 | 0.85 | ELANE (0.61) | BCL9CTNNB1GAAMGLLALDH1A1 | |
| SCHEMBL28101844 | 0.84 | BCL9 (0.50) | BCL9CTNNB1GAAMGLLALDH1A1 | |
| SCHEMBL3310085 | 0.83 | GAA (0.58) | BCL9CTNNB1GAAMGLLALDH1A1 | |
| SCHEMBL3101316 | 0.83 | BCL9 (0.56) | BCL9CTNNB1GAAMGLLALDH1A1 | |
| SCHEMBL20931042 | 0.83 | BCL9 (0.59) | BCL9CTNNB1GAAMGLLALDH1A1 | |
| SCHEMBL21853704 | 0.82 | GAA (0.57) | BCL9CTNNB1GAAMGLLALDH1A1 | |
| SCHEMBL27301103 | 0.82 | GAA (0.57) | BCL9CTNNB1GAAMGLLALDH1A1 | |
| SCHEMBL12691183 | 0.82 | ELANE (0.54) | BCL9CTNNB1GAAMGLLALDH1A1 | |
| SCHEMBL734833 | 0.81 | GAA (0.56) | BCL9CTNNB1GAAMGLLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11123304-B2 | Nanoparticles having poly(ester amide) polymer cores as drug delivery vehicles | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2021-09-21 | — | — | US | disclosed |
| US-20190350870-A1 | Particles as Delivery Systems | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-11-21 | — | — | US | disclosed |
| US-20140213738-A1 | POLY(ESTER AMIDE)S AND POLY(ESTER ETHER AMIDE)S WITH ALIPHATIC POLYESTERS, METHOD OF MAKING SAME, AND USES THEREOF | CORNELL UNIVERSITY (US) | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11123304-B2 | Nanoparticles having poly(ester amide) polymer cores as drug delivery vehicles | ASGR1, F12, MSR1 | BCL9 2435/4885CTNNB1 4391/4885GAA 465/4885 |
| US-20190350870-A1 | Particles as Delivery Systems | MTREX, APOB, HDLBP | BCL9 1961/4885CTNNB1 4310/4885GAA 1058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.