Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 10/20 | 0.36 |
| ▸ | THRB | P10828 | 10/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1743025 | 0.82 | CYP4A11 (0.39) | THRATHRBFAAHPTGS1RXRA | |
| SCHEMBL18116191 | 0.76 | HDAC1 (0.35) | — | |
| SCHEMBL4090552 | 0.75 | CA1 (0.43) | — | |
| SCHEMBL3680728 | 0.74 | THRA (0.50) | THRATHRB | |
| SCHEMBL558113 | 0.74 | HDAC1 (0.38) | — | |
| SCHEMBL557859 | 0.74 | HDAC1 (0.38) | — | |
| SCHEMBL557472 | 0.74 | HDAC1 (0.38) | — | |
| SCHEMBL557865 | 0.74 | HDAC1 (0.38) | — | |
| SCHEMBL4182737 | 0.73 | KMT2A (0.31) | — | |
| SCHEMBL4076440 | 0.72 | ITGB3 (0.42) | RXRANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796205-B2 | Insulin derivative | NOVO NORDISK A/S (DK) | 2014-08-05 | — | — | US | disclosed |