SCHEMBL159093

SCHEMBL159093

CCC(CC)c1ccc(N)cc1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 3/20 0.43
ALDH1A1 P00352 7/20 0.40
GAA P10253 6/20 0.40
MAPT P10636 5/20 0.40
KDM4E B2RXH2 4/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
TP53 P04637 2/20 0.40
USP2 O75604 2/20 0.40
POLB P06746 2/20 0.40
HTT P42858 2/20 0.40
CASP7 P55210 1/20 0.40
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 4/20 0.37
TSHR P16473 5/20 0.35
CYP3A4 P08684 3/20 0.35
PRKCI P41743 1/20 0.33
HPGD P15428 2/20 0.32
HSD17B10 Q99714 2/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3187941 0.83 CASP1 (0.38) CASP1ALDH1A1GAAMAPTKDM4E
SCHEMBL111964 0.83 CASP1 (0.43) CASP1ALDH1A1GAAMAPTKDM4E
SCHEMBL10885125 0.81 ALDH1A1 (0.38) CASP1ALDH1A1GAAMAPTKDM4E
SCHEMBL1772000 0.81 GAA (0.43) CASP1ALDH1A1GAAMAPTKDM4E
Hydrochloric Acid SCHEMBL8334339 0.81 GAA (0.39) CASP1ALDH1A1GAAMAPTKDM4E
SCHEMBL27668309 0.79 ALDH1A1 (0.40) ALDH1A1GAAHTTL3MBTL1
SCHEMBL28706266 0.78 CASP1 (0.39) CASP1ALDH1A1GAAMAPTKDM4E
SCHEMBL11511082 0.76 GAA (0.40) CASP1ALDH1A1GAAMAPTKDM4E
SCHEMBL10492816 0.76 CYP3A4 (0.40) CASP1ALDH1A1GAAMAPTKDM4E
SCHEMBL25676400 0.76 GAA (0.56) ALDH1A1GAAMAPTKDM4EUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 373 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107011925-B Material for liquid crystal vertical alignment film, liquid crystal box prepared from material and preparation method 成都海亿科技有限公司 2020-12-29 CN claimed
US-20200269094-A1 METHODS AND COMPOSITIONS FOR CROSS-LINKING THERMOPLASTIC POLYURETHANE COVERS FOR GOLF BALLS ACUSHNET COMPANY (US) 2020-08-27 US claimed
US-10570244-B2 Cross-linked thermoplastic co-polyester elastomer, method of making same, and articles composed thereof PENNSY CORPORATION (US) 2020-02-25 US claimed
CN-108219379-A A kind of integrated circuit plate modified epoxy and preparation method thereof 合肥东恒锐电子科技有限公司 2018-06-29 CN claimed
US-9950216-B2 Golf ball with softer feel and higher iron spin TAYLOR MADE GOLF COMPANY, INC. (US) 2018-04-24 US claimed
US-20140046002-A1 CROSS-LINKED THERMOPLASTIC CO-POLYESTER ELASTOMER, METHOD OF MAKING SAME, AND ARTICLES COMPOSED THEREOF PENNSY CORPORATION (US) 2014-02-13 US claimed
US-7879968-B2 Polymer compositions and golf balls with reduced yellowing TAYLOR MADE GOLF COMPANY, INC. (US) 2011-02-01 US claimed
US-20100323056-A1 CROSS-LINKED THERMOPLASTIC POLYURETHANE/POLYUREA AND METHOD OF MAKING SAME CALLAWAY GOLF COMPANY (US) 2010-12-23 US claimed
US-20100303950-A1 CROSS-LINKED THERMOPLASTIC POLYURETHANE/POLYUREA AND METHOD OF MAKING SAME CALLAWAY GOLF COMPANY (US) 2010-12-02 US claimed
US-7785522-B2 Cross-linked thermoplastic polyurethane/polyurea and method of making same PRIPRO POLYMERS, INC. (US) 2010-08-31 US claimed
US-20020098914-A1 Polyurethane covered three-piece golf ball TAYLOR MADE GOLF COMPANY, INC. 2002-07-25 US claimed
US-20020039935-A1 Golf ball having a non-yellowing cover OGIO INTERNATIONAL, INC. 2002-04-04 US claimed
EP-1120134-A2 Polyurethane covered three-piece golf ball Dunlop Slazenger Group Americas Inc (US) 2001-08-01 EP claimed
US-6190268-B1 COMPOSED OF A BLEND OF POLYURETHANE PREPOLYMERS CALLAWAY GOLF COMPANY 2001-02-20 US claimed
EP-0977617-A4 POLYURETHANE MATERIAL FOR TWO AND THREE PIECE GOLF BALLS AND METHOD DUNLOP MAXFLI SPORTS CORP (US) 2000-02-09 EP claimed
EP-0977617-A1 POLYURETHANE BASED TWO AND THREE PIECE GOLF BALLS Dunlop Slazenger Group Americas Inc (US) 2000-02-09 EP claimed
EP-0973585-A1 POLYURETHANE MATERIAL FOR TWO AND THREE PIECE GOLF BALLS Dunlop Slazenger Group Americas Inc (US) 2000-01-26 EP claimed
EP-0973585-A4 POLYURETHANE MATERIAL FOR TWO AND THREE PIECE GOLF BALLS DUNLOP MAXFLI SPORTS CORP (US) 2000-01-26 EP claimed
WO-1999043394-A1 POLYURETHANE MATERIAL FOR TWO AND THREE PIECE GOLF BALLS AND METHOD DUNLOP MAXFLI SPORTS CORPORATION (US) 1999-09-02 WO claimed
WO-1998037929-A1 POLYURETHANE MATERIAL FOR TWO AND THREE PIECE GOLF BALLS DUNLOP MAXFLI SPORTS CORPORATION (US) 1998-09-03 WO claimed