SCHEMBL15909803

SCHEMBL15909803

c1ccc(-c2cc3ccc4cc(-c5ccc6c(c5)oc5cc(N(c7ccccc7)c7cccnc7)ccc56)cc5ccc(c2)c3c45)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 8/20 0.39
CYP11B1 P15538 7/20 0.39
CYP11B2 P19099 7/20 0.39
CYP17A1 P05093 2/20 0.39
PGR P06401 1/20 0.37
PIM1 P11309 1/20 0.37
PIM2 Q9P1W9 1/20 0.37
CYP1A2 P05177 2/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
HSD17B1 P14061 1/20 0.34
CYP2B6 P20813 1/20 0.34
CYP2C19 P33261 1/20 0.34
HSD17B2 P37059 1/20 0.34
ERN1 O75460 1/20 0.34
GRM2 Q14416 1/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
KDM4E B2RXH2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15909808 0.96 CYP11B2 (0.45) CYP19A1CYP11B1CYP11B2CYP17A1PGR
SCHEMBL15909819 0.90 CYP11B2 (0.44) CYP19A1CYP11B1CYP11B2CYP17A1PGR
SCHEMBL15909785 0.86 CYP11B2 (0.50) CYP19A1CYP11B1CYP11B2CYP17A1NPC1
SCHEMBL15909779 0.86 CYP11B2 (0.47) CYP19A1CYP11B1CYP11B2CYP17A1NPC1
SCHEMBL15909763 0.86 CYP11B2 (0.47) CYP19A1CYP11B1CYP11B2CYP17A1NPC1
SCHEMBL15909824 0.85 CYP11B2 (0.42) CYP19A1CYP11B1CYP11B2CYP17A1PGR
SCHEMBL21203558 0.83 PGR (0.42) PGRCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL21203618 0.82 ESR1 (0.41) PGRCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL15909798 0.82 PGR (0.35) PGRPRKDC
SCHEMBL21203674 0.82 PGR (0.43) PGRHSD17B1HSD17B2PRKDCKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997713-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-12 US disclosed
US-9997713-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-12 US disclosed
US-20140209875-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed
US-20140209875-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed