SCHEMBL15909809

SCHEMBL15909809

N#Cc1ccc(N(c2ccc(-c3cc4ccc5cc(-c6ccccn6)cc6ccc(c3)c4c56)cc2)c2cccc3ccccc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.38
GRM5 P41594 7/20 0.37
TGFBR1 P36897 2/20 0.36
MAPK13 O15264 1/20 0.36
MAPK12 P53778 1/20 0.36
MAPK11 Q15759 1/20 0.36
MAPK14 Q16539 1/20 0.36
METAP2 P50579 1/20 0.35
METAP1 P53582 1/20 0.35
TDO2 P48775 1/20 0.35
ABCG2 Q9UNQ0 1/20 0.35
KCNH2 Q12809 1/20 0.34
PDPK1 O15530 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
PARP1 P09874 1/20 0.34
FFAR1 O14842 1/20 0.34
PIM1 P11309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15909762 0.87 CA1 (0.40) ABCG2PDPK1CA1CA2PARP1
SCHEMBL15909773 0.87 CA1 (0.40) ABCG2PDPK1CA1CA2PARP1
SCHEMBL15909804 0.86 GRM5 (0.42) GRM5TGFBR1MAPK13MAPK12MAPK11
SCHEMBL15909814 0.86 HRH3 (0.39) ABCG2PDPK1CA1CA2PARP1
SCHEMBL15909761 0.84 CA1 (0.39) ABCG2PDPK1CA1CA2
SCHEMBL15909778 0.83 HRH3 (0.37) ABCG2PDPK1CA1CA2PIM1
SCHEMBL15909822 0.83 CA1 (0.36) ABCG2PDPK1CA1CA2PARP1
SCHEMBL17690906 0.81 CA1 (0.41) HTR2CTDO2ABCG2PDPK1CA1
SCHEMBL25544771 0.81 CA1 (0.41) HTR2CTDO2ABCG2PDPK1CA1
SCHEMBL15909772 0.80 GRM5 (0.43) GRM5TGFBR1MAPK13MAPK12MAPK11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997713-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-12 US disclosed
US-9997713-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-12 US disclosed
US-20140209875-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed
US-20140209875-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed