SCHEMBL15909772

SCHEMBL15909772

N#Cc1ccc(N(c2ccccc2)c2cc3ccc4cc(-c5ccccn5)cc5ccc(c2)c3c45)cc1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 11/20 0.43
METAP2 P50579 1/20 0.40
METAP1 P53582 1/20 0.40
KCNH2 Q12809 1/20 0.39
TGFBR1 P36897 2/20 0.39
MAPK13 O15264 1/20 0.39
MAPK12 P53778 1/20 0.39
MAPK11 Q15759 1/20 0.39
MAPK14 Q16539 1/20 0.39
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
FFAR1 O14842 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15909804 0.94 GRM5 (0.42) GRM5METAP2METAP1KCNH2TGFBR1
SCHEMBL15909670 0.85 GRM5 (0.37) GRM5METAP2METAP1KCNH2TGFBR1
SCHEMBL20243301 0.83 MYC (0.39) LMNASMN1; SMN2PTGDR2
SCHEMBL15909809 0.80 HTR2C (0.38) GRM5METAP2METAP1KCNH2TGFBR1
SCHEMBL15909741 0.80 KDM4E (0.40) LMNASMN1; SMN2PTGDR2
SCHEMBL19788120 0.80 DHODH (0.39) METAP1LMNAHTTSMN1; SMN2
SCHEMBL15909752 0.79 CYP11B2 (0.48)
SCHEMBL15909753 0.78 ALDH1A1 (0.39) LMNASMN1; SMN2PTGDR2
SCHEMBL15909777 0.77 MYC (0.44) PTGDR2
SCHEMBL15909747 0.77 SMN1; SMN2 (0.38) METAP1TGFBR1LMNAHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997713-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-12 US disclosed
US-9997713-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-12 US disclosed
US-20140209875-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed
US-20140209875-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed