SCHEMBL15909804

SCHEMBL15909804

N#Cc1ccc(N(c2ccccc2)c2ccc(-c3cc4ccc5cc(-c6ccccn6)cc6ccc(c3)c4c56)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 7/20 0.42
TGFBR1 P36897 2/20 0.40
MAPK13 O15264 1/20 0.40
MAPK12 P53778 1/20 0.40
MAPK11 Q15759 1/20 0.40
MAPK14 Q16539 1/20 0.40
METAP2 P50579 1/20 0.39
METAP1 P53582 1/20 0.39
MYC P01106 1/20 0.39
KCNH2 Q12809 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA3 P34903 1/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
FFAR1 O14842 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15909772 0.94 GRM5 (0.43) GRM5TGFBR1MAPK13MAPK12MAPK11
SCHEMBL15909670 0.90 GRM5 (0.37) GRM5TGFBR1MAPK13MAPK12MAPK11
SCHEMBL15909809 0.86 HTR2C (0.38) GRM5TGFBR1MAPK13MAPK12MAPK11
SCHEMBL15909777 0.85 MYC (0.44) MYCPTGDR2GABRA1GABRG2GABRB3
SCHEMBL20243301 0.82 MYC (0.39) MYCPTGDR2GABRA1GABRG2GABRB3
SCHEMBL15909813 0.81 PTGDR2 (0.48) MYCPTGDR2GABRA1GABRG2GABRB3
SCHEMBL15909783 0.81 HRH3 (0.43) MYCPTGDR2GABRA1GABRG2GABRB3
SCHEMBL15909807 0.81 CYP2A6 (0.51) GRM5SMN1; SMN2
SCHEMBL15909769 0.81 CYP11B2 (0.52) MYCGABRA1GABRG2GABRB3GABRA5
SCHEMBL15909781 0.81 CYP11B2 (0.52) MYCGABRA1GABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997713-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-12 US disclosed
US-9997713-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-12 US disclosed
US-20140209875-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed
US-20140209875-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed