Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17724543 | 0.76 | TSHR (0.47) | ALDH1A1TSHRLMNA | |
| SCHEMBL29095033 | 0.73 | DGAT1 (0.42) | ALDH1A1 | |
| SCHEMBL5806950 | 0.73 | GAA (0.32) | GAA | |
| SCHEMBL17065142 | 0.71 | LMNA (0.33) | GAALMNA | |
| SCHEMBL19542033 | 0.67 | — | — | |
| SCHEMBL14592640 | 0.67 | GAA (0.42) | GAAALDH1A1TSHR | |
| SCHEMBL3257772 | 0.65 | LMNA (0.46) | GAAALDH1A1TSHRLMNA | |
| SCHEMBL43148 | 0.65 | — | — | |
| SCHEMBL3229564 | 0.65 | — | — | |
| SCHEMBL124447 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150291618-A1 | CARBAMOYLPYRIDONE DERIVATIVES | CONCERT PHARMACEUTICALS INC (US) | 2015-10-15 | — | — | US | disclosed |
| US-20140213553-A1 | CARBAMOYLPYRIDONE DERIVATIVES | CONCERT PHARMACEUTICALS INC. (US) | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213553-A1 | CARBAMOYLPYRIDONE DERIVATIVES | IDH1, CDKN1A, TYMP | GAA 383/4885ALDH1A1 1171/4885TSHR 4698/4885 |
| US-20150291618-A1 | CARBAMOYLPYRIDONE DERIVATIVES | CDKN1A, IDH1, IMPDH1 | GAA 424/4885ALDH1A1 506/4885TSHR 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.