Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.35 |
| ▸ | ANPEP | P15144 | 4/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15910556 | 1.00 | SLC7A5 (0.41) | SLC7A5SLC1A3SLC1A2GPR88ANPEP | |
| SCHEMBL1025811 | 0.86 | MEN1 (0.33) | MAPT | |
| Hydrochloric Acid SCHEMBL4854700 | 0.84 | MEN1 (0.33) | MAPT | |
| SCHEMBL1024449 | 0.81 | MEN1 (0.31) | MAPT | |
| SCHEMBL20974094 | 0.81 | MEN1 (0.31) | MAPT | |
| SCHEMBL18983137 | 0.81 | MEN1 (0.31) | MAPT | |
| SCHEMBL203296 | 0.80 | GABRP (0.37) | SLC7A5SLC1A3SLC1A2SLC1A1MAPT | |
| SCHEMBL1248340 | 0.80 | GABRP (0.37) | SLC7A5SLC1A3SLC1A2SLC1A1MAPT | |
| SCHEMBL3341769 | 0.79 | CACNA2D1 (0.50) | SLC7A5SLC1A3SLC1A2RNPEPCACNA2D1 | |
| SCHEMBL20679747 | 0.78 | ALDH1A1 (0.41) | SLC1A3SLC1A2SLC1A1ADRA1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2762476-A1 | 1,2,4-TRIAZINE-6-CARBOXAMIDE DERIVATIVE | Taiho Pharmaceutical Co., Ltd. (JP) | 2014-08-06 | — | — | EP | disclosed |