Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | YWHAG | P61981 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23286931 | 0.86 | RAB9A (0.49) | RAB9ACAMK2AALDH1A1KMT2ASRD5A1 | |
| SCHEMBL31730735 | 0.84 | RAB9A (0.48) | RAB9ACAMK2AALDH1A1KMT2ASRD5A1 | |
| SCHEMBL15919083 | 0.81 | RAB9A (0.43) | RAB9ACAMK2AALDH1A1KMT2ATSHR | |
| SCHEMBL7091098 | 0.78 | CAMK2A (0.39) | RAB9ACAMK2AKMT2ASRD5A1HSD17B3 | |
| SCHEMBL9682910 | 0.78 | RAB9A (0.56) | RAB9AALDH1A1KMT2ATSHRMAPT | |
| SCHEMBL31394626 | 0.76 | SRD5A1 (0.39) | RAB9ACAMK2ASRD5A1YWHAG | |
| SCHEMBL27285662 | 0.76 | CAMK2A (0.42) | RAB9ACAMK2ASRD5A1SRD5A2HTT | |
| SCHEMBL5090662 | 0.74 | MAPT (0.43) | RAB9ACAMK2AALDH1A1KMT2ASRD5A1 | |
| SCHEMBL5093605 | 0.74 | MAPT (0.43) | RAB9ACAMK2AALDH1A1KMT2ASRD5A1 | |
| SCHEMBL30956265 | 0.73 | MEN1 (0.34) | RAB9AKMT2AHTTMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140213538-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. | 2014-07-31 | — | — | US | disclosed |
| US-20140200215-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. | 2014-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213538-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | LPAR1, LPAR2, LPAR5 | RAB9A 2005/4885CAMK2A 1529/4885ALDH1A1 4135/4885 |
| US-20140200215-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | LPAR1, LPAR2, LPAR5 | RAB9A 2005/4885CAMK2A 1529/4885ALDH1A1 4135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.