Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | YWHAG | P61981 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20700070 | 0.85 | NCEH1 (0.39) | CAMK2ARAB9ASRD5A1HTTMAPT | |
| SCHEMBL15912427 | 0.78 | RAB9A (0.48) | CAMK2ARAB9ASRD5A1HSD17B3HTT | |
| SCHEMBL27787753 | 0.75 | SRD5A1 (0.44) | CAMK2ASRD5A1HSD17B3MAPK1MEN1 | |
| SCHEMBL31730735 | 0.75 | RAB9A (0.48) | CAMK2ARAB9ASRD5A1HTTMAPT | |
| SCHEMBL20700449 | 0.75 | NCEH1 (0.39) | RAB9ARECQL | |
| SCHEMBL23286931 | 0.74 | RAB9A (0.49) | CAMK2ARAB9ASRD5A1HTTMAPT | |
| SCHEMBL27571543 | 0.73 | SRD5A1 (0.33) | CAMK2ASRD5A1HTTMAPTLMNA | |
| SCHEMBL31394626 | 0.72 | SRD5A1 (0.39) | CAMK2ARAB9ASRD5A1YWHAG | |
| SCHEMBL27285662 | 0.72 | CAMK2A (0.42) | CAMK2ARAB9ASRD5A1HTTMAPT | |
| SCHEMBL15919083 | 0.72 | RAB9A (0.43) | CAMK2ARAB9AHTTMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345930-A2 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050067-A2 | PHARMACEUTICAL HETEROCYCLIC COMPOUNDS | ELI LILLY AND COMPANY (US) | 2002-06-27 | — | — | WO | disclosed |