SCHEMBL15912434

SCHEMBL15912434

NC(=O)CNC(=O)CCC(=O)N[C@H](CCC(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GNPAT O15228 1/20 0.54
FOLH1 Q04609 9/20 0.53
NAALAD2 Q9Y3Q0 3/20 0.53
RIMKLA Q8IXN7 1/20 0.53
EPHX2 P34913 1/20 0.44
NOD1 Q9Y239 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24235568 0.88 FOLH1 (0.58) GNPATFOLH1NAALAD2RIMKLAEPHX2
SCHEMBL17384176 0.86 FOLH1 (0.60) GNPATFOLH1NAALAD2RIMKLAEPHX2
SCHEMBL14310838 0.84 FOLH1 (0.72) GNPATFOLH1NAALAD2RIMKLAEPHX2
SCHEMBL7046532 0.83 GNPAT (0.65) GNPATFOLH1NAALAD2RIMKLANOD1
SCHEMBL1533825 0.82 FOLH1 (0.69) GNPATFOLH1NAALAD2RIMKLAEPHX2
SCHEMBL6270974 0.82 FOLH1 (0.69) GNPATFOLH1NAALAD2RIMKLAEPHX2
SCHEMBL16565941 0.81 GNPAT (0.58) GNPATFOLH1NAALAD2RIMKLAEPHX2
SCHEMBL21360278 0.81 FOLH1 (0.58) GNPATFOLH1NAALAD2RIMKLAEPHX2
SCHEMBL7047615 0.81 GNPAT (0.56) GNPATFOLH1NAALAD2RIMKLANOD1
SCHEMBL24208493 0.80 NOD1 (0.52) GNPATFOLH1NAALAD2RIMKLAEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160058873-A1 Cyclodextrin-Based Polymers for Therapeutic Delivery CERULEAN PHARMA INC (US) 2016-03-03 US disclosed
US-20140213504-A1 Cyclodextrin-Based Polymers for Therapeutic Delivery CERULEAN PHARMA INC. (US) 2014-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160058873-A1 Cyclodextrin-Based Polymers for Therapeutic Delivery IAPP, PRCP, DDOST GNPAT 966/4885FOLH1 164/4885NAALAD2 450/4885
US-20140213504-A1 Cyclodextrin-Based Polymers for Therapeutic Delivery IAPP, PRCP, DDOST GNPAT 966/4885FOLH1 164/4885NAALAD2 450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.