Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PNLIP | P16233 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15897450 | 0.86 | AKR1C3 (0.43) | CYP2C9CYP2C19CYP3A4AKR1A1AKR1B1 | |
| SCHEMBL15912486 | 0.85 | FFAR4 (0.49) | CYP1A2KMT2AALDH1A1PNLIPLMNA | |
| SCHEMBL7755868 | 0.81 | LMNA (0.51) | MAOBMAOAKMT2AALDH1A1LMNA | |
| SCHEMBL19524135 | 0.79 | SCN8A (0.58) | MAOBMAOAPNLIPLMNASCN8A | |
| SCHEMBL12726142 | 0.79 | KMT2A (0.47) | MAOBMAOAKMT2AALDH1A1PNLIP | |
| SCHEMBL7755864 | 0.78 | PTGDR2 (0.48) | MAOBMAOAKMT2ALMNAPTGDR2 | |
| SCHEMBL9367885 | 0.78 | PTGER4 (0.51) | MAOBMAOACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19513719 | 0.77 | NCEH1 (0.49) | MAOBMAOACYP1A2CYP2C19KMT2A | |
| SCHEMBL15897499 | 0.77 | SCN8A (0.47) | KMT2ASCN8ASCN10AHPGD | |
| SCHEMBL12726149 | 0.76 | POLB (0.46) | MAOBMAOACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140213538-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213538-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | LPAR1, LPAR2, LPAR5 | MAOB 2997/4885MAOA 2268/4885CYP1A2 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.