Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.51 |
| ▸ | SCN8A | Q9UQD0 | 11/20 | 0.50 |
| ▸ | SCN10A | Q9Y5Y9 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | PNLIP | P16233 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19524223 | 0.90 | SCN8A (0.56) | PTGER4PTGER2SCN8ASCN10ASMN1; SMN2 | |
| SCHEMBL19524169 | 0.85 | SCN8A (0.60) | SCN8ASCN10A | |
| SCHEMBL5310179 | 0.85 | HTR2A (0.54) | SCN8ASCN10APNLIP | |
| SCHEMBL19524218 | 0.84 | SCN8A (0.62) | PTGER4PTGER2SCN8ASCN10AALDH1A1 | |
| SCHEMBL19524204 | 0.84 | SCN8A (0.53) | SCN8ASCN10AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL4445272 | 0.84 | PTGER4 (0.59) | PTGER4PTGER2SCN8ASCN10APNLIP | |
| SCHEMBL24981345 | 0.83 | GRM5 (0.46) | SCN8ASCN10AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL43492 | 0.80 | PIN1 (0.49) | ALDH1A1HTTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL5756844 | 0.79 | CFD (0.51) | ALDH1A1HTTSMN1; SMN2CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL8640823 | 0.78 | BACE1 (0.46) | PTGER4PTGER2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365915-B1 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1994-04-20 | — | — | EP | disclosed |
| US-4956370-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |
| EP-0365915-A2 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1990-05-02 | — | — | EP | disclosed |