SCHEMBL15915437

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5611920	0.92	KMT2A (0.41)	ALOX15KMT2ABLMPMP22EPHX1
	SCHEMBL2844179	0.89	KMT2A (0.41)	ALOX15KMT2ABLMPMP22EPHX1
	SCHEMBL9517412	0.83	AKR1B1 (0.44)	ALOX15KMT2AMEN1LMNAGABRP
	SCHEMBL30104283	0.82	FAAH (0.59)	ALOX15KMT2ABLMCYP1A2MEN1
	SCHEMBL7026501	0.82	NOS1 (0.39)	ALOX15KMT2ABLMEPHX1CYP1A2
	SCHEMBL8430447	0.79	CYP1A2 (0.53)	ALOX15KMT2ACYP1A2CYP3A4CYP2C19
	SCHEMBL27563607	0.79	CA1 (0.35)	ALOX15KMT2ABLMPMP22CYP1A2
	SCHEMBL8434211	0.79	TSHR (0.54)	KMT2AEPHX1CYP1A2MEN1LMNA
	SCHEMBL28741965	0.79	CA1 (0.35)	ALOX15KMT2AEPHX1CYP1A2MEN1
	SCHEMBL26133367	0.79	CA1 (0.35)	ALOX15KMT2ABLMPMP22CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.